Utilization of a Recombinant Substrate rAgg1 to Study the Biochemical Properties of Aggrecanase in Cell Culture Systems (Q57539967)

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5 November 2019

title

Utilization of a recombinant substrate rAgg1 to study the biochemical properties of aggrecanase in cell culture systems (English)

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5 November 2019

1

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5 November 2019

Bruce Caterson

series ordinal

4

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5

E Bartnik

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5 November 2019

author name string

F H Büttner

series ordinal

2

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5 November 2019

B Eidenmüller

series ordinal

3

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5 November 2019

language of work or name

English

0 references

publication date

1 August 1997

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Journal of Biological Chemistry

5 November 2019

published in

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volume

272

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5 November 2019

issue

32

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5 November 2019

page(s)

20269-20274

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Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

5 November 2019

cites work

1 reference

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Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

21 January 2018

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Degradation of proteoglycan in articular cartilage

21 January 2018

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Chondrocyte-mediated depletion of articular cartilage proteoglycans in vitro

21 January 2018

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Mechanism of catabolism of aggrecan by articular cartilage

21 January 2018

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N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

21 January 2018

1 reference

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The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan

21 January 2018

1 reference

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Extraction and isolation of mRNA from adult articular cartilage

21 January 2018

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CD44 is the principal cell surface receptor for hyaluronate

21 January 2018

1 reference

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High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

Extracellular matrix metabolism by chondrocytes III. Modulation of proteoglycan synthesis by extracellular levels of proteoglycan in cartilage cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

Structure of the human aggrecan gene: exon-intron organization and association with the protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.32.20269

21 January 2018

Identifiers

DOI

10.1074/JBC.272.32.20269

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9242707%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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