Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab (Q57569257)

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9 November 2019

title

Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab (English)

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9 November 2019

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2

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9 November 2019

author name string

S Mascheretti

1

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9 November 2019

T Kühbacher

3

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9 November 2019

H Herfarth

4

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9 November 2019

M Krawczak

5

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9 November 2019

U R Fölsch

6

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S Schreiber

7

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9 November 2019

publication date

1 January 2002

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The Pharmacogenomics Journal

9 November 2019

published in

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9 November 2019

volume

2

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9 November 2019

issue

2

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9 November 2019

page(s)

127-136

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https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500091

9 November 2019

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Chimeric anti-TNF-α monoclonal antibody cA2 binds recombinant transmembrane TNF-α and activates immune effector functions

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A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor

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Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization

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Physical mapping and genomic structure of the human TNFR2 gene

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An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles

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Infliximab for the treatment of fistulas in patients with Crohn's disease

21 January 2018

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A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria

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Crohn's disease is associated with novel polymorphisms in the 5'-flanking region of the tumor necrosis factor gene

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Model-free analysis and permutation tests for allelic associations.

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Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

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A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort

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Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci

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Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses

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Linkage of inflammatory bowel disease to human chromosome 6p

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A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis

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Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

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ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease

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Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease

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Distribution of four polymorphisms in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD)

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Identifiers

DOI

10.1038/SJ.TPJ.6500091

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12049175%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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