An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis (Q57570913)

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7 November 2019

title

An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis (English)

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7 November 2019

2

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7 November 2019

author name string

J J Cho

1

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7 November 2019

H Herbst

3

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7 November 2019

J D Jia

4

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7 November 2019

M Ruehl

5

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7 November 2019

E G Hahn

6

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7 November 2019

E O Riecken

7

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7 November 2019

D Schuppan

8

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7 November 2019

language of work or name

English

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publication date

1 June 2000

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7 November 2019

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7 November 2019

volume

118

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7 November 2019

issue

6

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7 November 2019

page(s)

1169-1178

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Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies

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Effects and mechanisms of action of endothelins on non-vascular smooth muscle of the respiratory, gastrointestinal and urogenital tracts.

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?ndothelin: new discoveries and rapid progress in the clinic

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The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus

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Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo

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Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells

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The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin, and nitric oxide

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Cellular localization of endothelin-1 and increased production in liver injury in the rat: potential for autocrine and paracrine effects on stellate cells

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Activation of rat hepatic stellate cells in culture is associated with increased sensitivity to endothelin 1.

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Ito cell contraction in response to endothelin-1 and substance P

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Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1.

7 January 2021

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Detection of endothelin-1 and its receptors in rat liver endothelial cells by in situ reverse transcriptase-polymerase chain reaction.

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Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension.

7 January 2021

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Increased hepatic endothelin-1 levels and endothelin receptor density in cirrhotic rats

7 January 2021

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Plasma endothelin-1 and -3 in cirrhosis: relationship with systemic hemodynamics, renal function and neurohumoral systems

7 January 2021

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Endothelin and endothelin antagonists in hypertension

7 January 2021

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Elevated serum aminoterminal procollagen type-III-peptide parallels collagen accumulation in rats with secondary biliary fibrosis

7 January 2021

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Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats

7 January 2021

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Endothelin System–Dependent Cardiac Remodeling in Renovascular Hypertension

7 January 2021

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Serum concentration of the aminoterminal procollagen type III peptide in the rat reflects early formation of connective tissue in experimental liver cirrhosis.

7 January 2021

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A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues

7 January 2021

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Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D.

7 January 2021

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Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

7 January 2021

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Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis.

7 January 2021

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

7 January 2021

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Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway

7 January 2021

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Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B rec

7 January 2021

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LU 302 872 and its racemate (LU 224 332) show balanced endothelin-A/B receptor affinity, high oral activity, and inhibit human prostate tissue contractions

7 January 2021

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Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apolipoprotein E-deficient mice

7 January 2021

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7 January 2021

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7 January 2021

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Different contributions of endothelin-A and endothelin-B receptors in the pathogenesis of deoxycorticosterone acetate-salt-induced hypertension in rats

7 January 2021

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Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential

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7 January 2021

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7 January 2021

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7 January 2021

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Chronic blockade of endothelin ETA receptors improves flow dependent dilation in resistance arteries of hypertensive rats.

7 January 2021

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EndothelinA receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension.

7 January 2021

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10.1016/S0016-5085(00)70370-2

7 January 2021

Identifiers

DOI

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7 November 2019

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