Rationale and Design of the MITOCARE Study: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of TRO40303 for the Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coro (Q57572076)

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article by MITOCARE Study Group published 2012 in Cardiology

Language	Label	Description	Also known as
English	Rationale and Design of the MITOCARE Study: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of TRO40303 for the Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coro	article by MITOCARE Study Group published 2012 in Cardiology

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scholarly article

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Rationale and Design of the MITOCARE Study: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of TRO40303 for the Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coro (English)

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reperfusion injury

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

MITOCARE Study Group

1

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language of work or name

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publication date

2012

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123

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4

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201-207

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Myocardial reperfusion injury.

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Postconditioning the human heart

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Effect of cyclosporine on reperfusion injury in acute myocardial infarction

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Effect of intravenous FX06 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction results of the F.I.R.E. (Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury) trial.

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Post-conditioning reduces infarct size and edema in patients with ST-segment elevation myocardial infarction

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Long-term benefit of postconditioning

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Cardioprotective effects of ischemic postconditioning in patients treated with primary percutaneous coronary intervention, evaluated by magnetic resonance.

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Ischaemic postconditioning revisited: lack of effects on infarct size following primary percutaneous coronary intervention

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Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis

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TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.

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The mitochondrial permeability transition pore and ischemia-reperfusion injury

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Mitochondrial permeability transition pore opening as a promising therapeutic target in cardiac diseases

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The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis

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Role of cardiac magnetic resonance imaging in ischaemic heart disease

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Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report

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Infarct evolution in man studied in patients with first-time coronary occlusion in comparison to different species - implications for assessment of myocardial salvage

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Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations.

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Myocardium at risk after acute infarction in humans on cardiac magnetic resonance: quantitative assessment during follow-up and validation with single-photon emission computed tomography.

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Assessment of myocardium at risk with contrast enhanced steady-state free precession cine cardiovascular magnetic resonance compared to single-photon emission computed tomography

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Automated quantification of myocardial infarction from MR images by accounting for partial volume effects: animal, phantom, and human study.

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Rapid Initial Reduction of Hyperenhanced Myocardium After Reperfused First Myocardial Infarction Suggests Recovery of the Peri-Infarction Zone

1 reference

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Acute myocardial infarction: serial cardiac MR imaging shows a decrease in delayed enhancement of the myocardium during the 1st week after reperfusion

1 reference

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10.1159/000342981

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