A Chimeric GPCR Model Mimicking the Ligand Binding Site of the Human Y1 Receptor Studied by NMR Spectroscopy (Q57794644)

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5 February 2020

title

A chimeric GPCR model mimicking the ligand binding site of the human Y1 receptor studied by NMR spectroscopy (English)

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5 February 2020

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5 February 2020

author name string

Reto Walser

series ordinal

1

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5 February 2020

Oliver Zerbe

series ordinal

3

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publication date

21 June 2011

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5 February 2020

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5 February 2020

volume

12

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issue

11

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page(s)

1690-1693

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describes a project that uses

5 February 2020

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The impact of GPCR structures on pharmacology and structure-based drug design

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GPCR agonists and antagonists in the clinic

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Crystal structure of rhodopsin: A G protein-coupled receptor

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Crystal structure of squid rhodopsin

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

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Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

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Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

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NMR Structure of the First Extracellular Domain of Corticotropin-releasing Factor Receptor 1 (ECD1-CRF-R1) Complexed with a High Affinity Agonist

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Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors

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Studies of the structure of the N-terminal domain from the Y4 receptor - a G protein-coupled receptor - and its interaction with hormones from the NPY family

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Are hormones from the neuropeptide Y family recognized by their receptors from the membrane-bound state?

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Structure of outer membrane protein A transmembrane domain by NMR spectroscopy

21 January 2018

1 reference

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Structure of the outer membrane protein A transmembrane domain

21 January 2018

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Association of neighboring β-strands of outer membrane protein A in lipid bilayers revealed by site-directed fluorescence quenching

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Membrane assembly of the Escherichia coli outer membrane protein OmpA: exploring sequence constraints on transmembrane beta-strands

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A minimal transmembrane beta-barrel platform protein studied by nuclear magnetic resonance

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Increasing the accuracy of solution NMR structures of membrane proteins by application of residual dipolar couplings. High-resolution structure of outer membrane protein A.

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1 reference

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Orientation of beta-barrel proteins OmpA and FhuA in lipid membranes. Chain length dependence from infrared dichroism

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1 reference

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Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles

21 January 2018

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Major Proteins of the Escherichia coli Outer Cell Envelope Membrane. Interaction of Protein II* with Lipopolysaccharide

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Outer membrane protein A of E. coli folds into detergent micelles, but not in the presence of monomeric detergent

21 January 2018

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2-36[K4,RYYSA(19-23)]PP a novel Y5-receptor preferring ligand with strong stimulatory effect on food intake.

21 January 2018

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Complete L-alanine scan of neuropeptide Y reveals ligands binding to Y1 and Y2 receptors with distinguished conformations

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Group epitope mapping by saturation transfer difference NMR to identify segments of a ligand in direct contact with a protein receptor

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Lipid-protein interactions in DHPC micelles containing the integral membrane protein OmpX investigated by NMR spectroscopy

21 January 2018

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Application of a Theory of Enzyme Specificity to Protein Synthesis

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Folding and binding cascades: shifts in energy landscapes

21 January 2018

1 reference

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Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1002/CBIC.201100244

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21695755%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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