Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins (Q57941803)

4

object named as

Eleftherios P. Diamandis

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Iacovos P Michael

object named as

Iacovos P. Michael

2

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author name string

Chistina V. Obiezu

1

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Michael A. Levesque

Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation

3

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publication date

1 January 2006

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published in

Biological Chemistry

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volume

387

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issue

6

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cites work

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The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers

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Stratum corneum chymotryptic enzyme in psoriasis

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Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region

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Exclusion of candidate genes in two families with autosomal dominant hypocalcified amelogenesis imperfecta

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Mutation in kallikrein 4 causes autosomal recessive hypomaturation amelogenesis imperfecta

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Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors

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Enamelysin and kallikrein-4 mRNA expression in developing mouse molars

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Structure of a serpin-protease complex shows inhibition by deformation

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Alpha 1-antitrypsin: structure, function and molecular biology of the gene

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Complex formation between human kallikrein 13 and serum protease inhibitors

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Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

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Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages

21 January 2018

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Distinctly different gene structure of KLK4/KLK-L1/prostase/ARM1 compared with other members of the kallikrein family: intracellular localization, alternative cDNA forms, and Regulation by multiple hormones

21 January 2018

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Pi-, delta-, and gamma-chymotrypsin: three-dimensional electron-density and difference maps at 5 A resolution, and comparison with chymotrypsinogen

21 January 2018

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Zyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brain

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Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors

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Structural characterization and mapping of the normal epithelial cell-specific 1 gene

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Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors

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Substrates of the prostate-specific serine protease prostase/KLK4 defined by positional-scanning peptide libraries

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Relative levels of mRNA encoding enamel proteins in enamel organ epithelia and odontoblasts

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Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression

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Proteolytic processing and physiological regulation

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Human and mouse proteases: a comparative genomic approach

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Human Kallikrein 2 (hK2) and prostate-specific antigen (PSA): two closely related, but distinct, kallikreins in the prostate

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Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts.

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The urokinase-type plasminogen activator system in prostate cancer metastasis

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Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4

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Characterization of the precursor of prostate-specific antigen. Activation by trypsin and by human glandular kallikrein.

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Characterization of hK4 (prostase), a prostate-specific serine protease: activation of the precursor of prostate specific antigen (pro-PSA) and single-chain urokinase-type plasminogen activator and degradation of prostatic acid phosphatase

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Structure and function of human tissue-type plasminogen activator (t-PA).

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Activation of chymotrypsinogen-A. An hypothesis based upon comparison of the crystal structures of chymotrypsinogen-A and alpha-chymotrypsin

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Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer

21 January 2018

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Serpins and other covalent protease inhibitors

21 January 2018

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Sequence analysis and expression of human neuropsin cDNA and gene.

21 January 2018

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The new kallikrein-like gene, KLK-L2. Molecular characterization, mapping, tissue expression, and hormonal regulation

21 January 2018

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The expanded human kallikrein gene family: locus characterization and molecular cloning of a new member, KLK-L3 (KLK9).

21 January 2018

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The new human tissue kallikrein gene family: structure, function, and association to disease.

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Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease

21 January 2018

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Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4.

21 January 2018

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The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation

21 January 2018

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Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family

21 January 2018

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KLK12 is a novel serine protease and a new member of the human kallikrein gene family-differential expression in breast cancer.

21 January 2018

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Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues

21 January 2018

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Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer

21 January 2018

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Role of kallikrein enzymes in the central nervous system

21 January 2018

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