Tertiary and quaternary conformational changes in aspartate transcarbamylase: a normal mode study (Q58008929)

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8 December 2019

title

Tertiary and quaternary conformational changes in aspartate transcarbamylase: a normal mode study (English)

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8 December 2019

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2

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8 December 2019

2

Konrad Hinsen

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author name string

Aline Thomas

1

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Martin J. Field

3

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David Perahia

4

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A Thomas

1

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8 December 2019

M J Field

3

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8 December 2019

D Perahia

4

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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8 December 2019

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8 December 2019

volume

34

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8 December 2019

issue

1

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8 December 2019

page(s)

96-112

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Analysis of the low frequency normal modes of the T-state of aspartate transcarbamylase.

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Analysis of the low-frequency normal modes of the R state of aspartate transcarbamylase and a comparison with the T state modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Structural asymmetry in the CTP-liganded form of aspartate carbamoyltransferase from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Unlike the quaternary structure transition, the tertiary structure change of the 240s loop in allosteric aspartate transcarbamylase requires active site saturation by substrate for completion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

A molecular mechanism for pyrimidine and purine nucleotide control of aspartate transcarbamoylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Escherichia coli aspartate carbamoyltransferase: the probing of crystal structure analysis via site-specific mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Domain closure in the catalytic chains of Escherichia coli aspartate transcarbamoylase influences the kinetic mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Importance of domain closure for homotropic cooperativity in Escherichia coli aspartate transcarbamylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Heterotropic effectors promote a global conformational change in aspartate transcarbamoylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Molecular dynamics simulations and rigid body (TLS) analysis of aspartate carbamoyltransferase: evidence for an uncoupled R state

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Normal mode analysis of human lysozyme: study of the relative motion of the two domains and characterization of the harmonic motion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Motions in hemoglobin studied by normal mode analysis and energy minimization: evidence for the existence of tertiary T-like, quaternary R-like intermediate structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Mechanisms of cooperativity and allosteric regulation in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Polar hydrogen positions in proteins: Empirical energy placement and neutron diffraction comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

The effects of truncating long-range forces on protein dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Computation of low-frequency normal modes in macromolecules: improvements to the method of diagonalization in a mixed basis and application to hemoglobin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

A solution for the best rotation to relate two sets of vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

A discussion of the solution for the best rotation to relate two sets of vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Dynamics of a small globular protein in terms of low-frequency vibrational modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Dynamic and elastic properties of F-actin: a normal-modes analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Model-free methods of analyzing domain motions in proteins from simulation: a comparison of normal mode analysis and molecular dynamics simulation of lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Rigid domains in proteins: an algorithmic approach to their identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Identification and analysis of domains in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Molecular dynamics study of time-correlated protein domain motions and molecular flexibility: cytochrome P450BM-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Heterotropic interactions in Escherichia coli aspartate transcarbamylase. Subunit interfaces involved in CTP inhibition and ATP activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

The activation of Escherichia coli aspartate transcarbamylase by ATP. Specific involvement of helix H2' at the hydrophobic interface between the two domains of the regulatory chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Arginine 54 in the active site of Escherichia coli aspartate transcarbamoylase is critical for catalysis: a site-specific mutagenesis, NMR, and X-ray crystallographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Relationship between domain closure and binding, catalysis, and regulation in Escherichia coli aspartate transcarbamylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Glu-50 in the catalytic chain of Escherichia coli aspartate transcarbamoylase plays a crucial role in the stability of the R quaternary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

The allosteric activator ATP induces a substrate-dependent alteration of the quaternary structure of a mutant aspartate transcarbamoylase impaired in active site closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Engineered complementation in Escherichia coli aspartate transcarbamoylase. Heterotropic regulation by quaternary structure stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

Identification and analysis of long-range electrostatic effects in proteins by computer modeling:aspartate transcarbamylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

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21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%2819990101%2934%3A1%3C96%3A%3AAID-PROT8%3E3.0.CO%3B2-0

10.1002/(SICI)1097-0134(19990101)34:1<96::AID-PROT8>3.0.CO;2-0

21 January 2018

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8 December 2019

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