Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients (Q58019241)

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4 November 2019

title

Secretory lysosome biogenesis in cytotoxic T lymphocytes from normal and Chediak Higashi syndrome patients (English)

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4 November 2019

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3

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4 November 2019

author name string

Stinchcombe JC

series ordinal

1

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4 November 2019

Page LJ

series ordinal

2

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4 November 2019

publication date

1 May 2000

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4 November 2019

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4 November 2019

volume

1

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4 November 2019

page(s)

435-444

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4 November 2019

issue

5

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Granzymes: exogenous proteinases that induce target cell apoptosis.

4 November 2019

cites work

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T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help

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Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

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Constitutive and regulated secretion of proteins

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Regulated secretion from hemopoietic cells

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The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments

21 January 2018

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The activation of resting lymphocytes is accompanied by the biogenesis of lysosomal organelles

21 January 2018

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Ultrastructural localization of a lysosomal enzyme in resin-embedded lymphocytes

21 January 2018

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Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway

21 January 2018

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Distribution of anomalous lysosomes in the beige mouse: a homologue of Chediak-Higashi syndrome

21 January 2018

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Identification of the homologous beige and Chediak-Higashi syndrome genes

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Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome

21 January 2018

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The Beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein

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Biosynthesis and transport of cathepsin D in cultured human fibroblasts

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Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

21 January 2018

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Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent

21 January 2018

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Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

21 January 2018

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Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome

21 January 2018

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Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing

21 January 2018

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The biogenesis of lysosomes: is it a kiss and run, continuous fusion and fission process?

21 January 2018

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Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

21 January 2018

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Anterograde and retrograde traffic between the rough endoplasmic reticulum and the Golgi complex

21 January 2018

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Complementation analysis of Chediak-Higashi Syndrome: The same gene may be responsible for the defect in all patients and species

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Molecules relevant for T cell-target cell interaction are present in cytolytic granules of human T lymphocytes

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Human large granular lymphocytes and natural killing ultrastructural studies of strontium-induced degranulation

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1034/J.1600-0854.2000.010508.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11208129%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference