Surgical systems biology and personalized longitudinal phenotyping in critical care (Q58045562)

6

0 references

Ara Darzi

object named as

Ara Darzi

5

0 references

author name string

Laura J Muirhead

1

0 references

Thomas S FitzMaurice

3

0 references

Zoltan Takats

Global systems biology, personalized medicine and molecular epidemiology

4

0 references

language of work or name

English

0 references

publication date

August 2012

0 references

published in

Personalized Medicine

0 references

volume

9

0 references

issue

6

0 references

page(s)

593-608

0 references

cites work

1 reference

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

Metabolic phenotyping in health and disease

21 January 2018

1 reference

Pharmaco-metabonomic phenotyping and personalized drug treatment

21 January 2018

1 reference

Metabonomics: a platform for studying drug toxicity and gene function

21 January 2018

1 reference

Ecological control of the gastrointestinal tract. The role of probiotic flora

21 January 2018

1 reference

Metagenomic analysis of the human distal gut microbiome

21 January 2018

1 reference

An ecological and evolutionary perspective on human-microbe mutualism and disease

21 January 2018

1 reference

21 January 2018

The Hallmarks of Cancer

1 reference

Integrated analysis reveals critical genomic regions in prostate tumor microenvironment associated with clinicopathologic phenotypes.

21 January 2018

1 reference

Microarray analysis of colorectal cancer stromal tissue reveals upregulation of two oncogenic miRNA clusters

21 January 2018

1 reference

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

21 January 2018

1 reference

Identification of collapsin response mediator protein-2 as a potential marker of colorectal carcinoma by comparative analysis of cancer cell secretomes

21 January 2018

1 reference

Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach

21 January 2018

1 reference

Genomewide association studies and assessment of the risk of disease

21 January 2018

1 reference

Genome-wide association study of acute post-surgical pain in humans

21 January 2018

1 reference

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

21 January 2018

1 reference

Universal noninvasive detection of solid organ transplant rejection

21 January 2018

1 reference

Explaining the decrease in mortality from abdominal aortic aneurysm rupture.

21 January 2018

1 reference

Predictors of mortality in adult trauma patients: the physiologic trauma score is equivalent to the Trauma and Injury Severity Score.

21 January 2018

1 reference

Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

21 January 2018

1 reference

Severe traumatic head injury affects systemic cytokine expression

21 January 2018

1 reference

21 January 2018

Preoperative assessment

1 reference

Fast-track vs standard care in colorectal surgery: a meta-analysis update

21 January 2018

1 reference

Impaired functional capacity is associated with all-cause mortality after major elective intra-abdominal surgery

21 January 2018

1 reference

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

21 January 2018

1 reference

Ecological and evolutionary forces shaping microbial diversity in the human intestine

21 January 2018

1 reference

Human gut microbiome adopts an alternative state following small bowel transplantation

21 January 2018

1 reference

Human gut microbiota in obesity and after gastric bypass

21 January 2018

1 reference

Global metabolic phenotyping in an experimental laparotomy model of surgical trauma

21 January 2018

1 reference

Effect of bowel preparation and colonoscopy on post-procedure intestinal microbiota composition

21 January 2018

1 reference

Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome

21 January 2018

1 reference

The effect of proton pump inhibitors on the human microbiota

21 January 2018

1 reference

Probiotics improve outcomes after Roux-en-Y gastric bypass surgery: a prospective randomized trial

21 January 2018

1 reference

Microbial ecology: human gut microbes associated with obesity

21 January 2018

1 reference

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

21 January 2018

1 reference

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

21 January 2018

1 reference

Gut microbiome-host interactions in health and disease

21 January 2018

1 reference

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

21 January 2018

1 reference

Gut microbiota: a potential new territory for drug targeting

21 January 2018

1 reference

Who benefits from nutritional support: what is the evidence?

21 January 2018

1 reference

Immunonutrition in high-risk surgical patients: a systematic review and analysis of the literature

21 January 2018

1 reference

Nutritional screening for risk prediction in patients scheduled for abdominal operations.

21 January 2018

1 reference

Development of the human infant intestinal microbiota

21 January 2018

1 reference

Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians

21 January 2018

1 reference

Systems biology: Metabonomics

21 January 2018

1 reference

Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues

21 January 2018

1 reference

An HR-MAS MR metabolomics study on breast tissues obtained with core needle biopsy

21 January 2018

1 reference

Identification of Biological Tissues by Rapid Evaporative Ionization Mass Spectrometry

21 January 2018

1 reference

Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

21 January 2018

1 reference

Ultrahighly sensitive in situ metabolomic imaging for visualizing spatiotemporal metabolic behaviors

21 January 2018

1 reference

Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology

21 January 2018

1 reference

G-DOC: a systems medicine platform for personalized oncology

21 January 2018

1 reference

Nutritional metabonomics: applications and perspectives

21 January 2018

1 reference

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

21 January 2018

1 reference

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

21 January 2018

1 reference

Unique characteristics of emergency care research: scope, populations, and infrastructure

21 January 2018

1 reference

Damage control resuscitation: a sensible approach to the exsanguinating surgical patient

21 January 2018

1 reference

Damage control resuscitation: directly addressing the early coagulopathy of trauma.

21 January 2018

1 reference

Emergency trauma score: an instrument for early estimation of trauma severity

21 January 2018

1 reference

Systemic metabolic changes of traumatic critically ill patients revealed by an NMR-based metabonomic approach

21 January 2018

1 reference

1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit

21 January 2018

1 reference

Long-term mortality after gastric bypass surgery

21 January 2018

1 reference

Metabolic surgery and cancer: protective effects of bariatric procedures

21 January 2018

1 reference

Gut microbiome-derived metabolites characterize a peculiar obese urinary metabotype.

21 January 2018

1 reference

Metabolite profiling identifies candidate markers reflecting the clinical adaptations associated with Roux-en-Y gastric bypass surgery

21 January 2018

1 reference

Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk.

21 January 2018

1 reference

Prevalence of prostate cancer among men with a prostate-specific antigen level < or =4.0 ng per milliliter

21 January 2018

1 reference

Prostate specific antigen for early detection of prostate cancer: longitudinal study

21 January 2018

1 reference

Screening for prostate cancer in 2008 II: the importance of molecular subforms of prostate-specific antigen and tissue kallikreins.

21 January 2018

1 reference

Candidate serum biomarkers for prostate adenocarcinoma identified by mRNA differences in prostate tissue and verified with protein measurements in tissue and blood

21 January 2018

1 reference

Urine biomarkers in prostate cancer

21 January 2018

1 reference

Measurement of GSTP1 promoter methylation in body fluids may complement PSA screening: a meta-analysis

21 January 2018

1 reference

Level of α-fetoprotein predicts mortality among patients with hepatitis C-related hepatocellular carcinoma

21 January 2018

1 reference

Diagnosing and monitoring hepatocellular carcinoma with alpha-fetoprotein: new aspects and applications

21 January 2018

1 reference

Combination of alpha-1-acid glycoprotein and alpha-fetoprotein as an improved diagnostic tool for hepatocellular carcinoma

21 January 2018

1 reference

Utility of Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein and des-gamma-carboxy prothrombin, alone or in combination, as biomarkers for hepatocellular carcinoma

21 January 2018

1 reference

21 January 2018

Carcinoembryonic antigen

1 reference

Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer

21 January 2018

1 reference

Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

21 January 2018

1 reference

The National Institute for Health and Clinical Excellence (NICE) guidelines for early detection of ovarian cancer: the pivotal role of the clinical laboratory.

21 January 2018

1 reference

CA 125, PET alone, PET-CT, CT and MRI in diagnosing recurrent ovarian carcinoma: a systematic review and meta-analysis

21 January 2018

1 reference

Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women

21 January 2018

1 reference

Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).

21 January 2018

1 reference

Potential role of HE4 in multimodal screening for epithelial ovarian cancer

21 January 2018

1 reference

Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer

21 January 2018

1 reference

Clinical usefulness of carbohydrate antigen 19-9 as a screening test for pancreatic cancer in an asymptomatic population

21 January 2018

1 reference

Clinical review: scoring systems in the critically ill.

21 January 2018

1 reference

Risk scoring in perioperative and surgical intensive care patients: a review

21 January 2018

1 reference

Comparison of Surgical Risk Score, POSSUM and p-POSSUM in higher-risk surgical patients.

21 January 2018

1 reference

Effectiveness of the PRISM III score for predicting mortality in pediatric intensive care neurologic patients

21 January 2018

1 reference

SAPS 3--From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission

21 January 2018

1 reference