Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect (Q58048926)

4

object named as

Christopher J. Schofield

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author name string

Jack E. Baldwin

1

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Robert M. Adlington

2

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Nicholas P. Crouch

3

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Nicholas J. Turner

5

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Robin T. Aplin

Incorporation of 3H and 14C from (6 alpha-3H)penicillin N and (10-14C,6 alpha-3H) penicillin N into deacetoxycephalosporin C

6

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publication date

December 1991

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published in

Tetrahedron

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volume

47

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issue

47

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page(s)

9881-9900

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cites work

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Incorporation of (2RS,3S)-[4-13C]-valine into cephalosporin C

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Synthesis and incorporation of (2S,3S)-(4-13C)valine into beta-lactam antibiotics

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Partial purification and catalytic properties of a bifunctional enzyme in the biosynthetic pathway of beta-lactams in Cephalosporium acremonium

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Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities

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Substrate specificity of cloned deacetoxycephalosporin C/deacetylcephalosporin C synthetase

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Stereochemistry of the incorporation of valine methyl groups into methylene groups in cephalosporin C.

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The enzymatic conversion of exomethylene cephalosporin c into deacetyl cephalosporin c and the role of molecular oxygen in cephalosporin c biosynthesis

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Enzymatic conversion of the unnatural tripeptide .DELTA.-(D-.ALPHA.-aminoadipyl)-L-cysteinyl-D-valine to .BETA.-lactam antibiotics

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Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N

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Synthesis of 7 beta-(5-D-aminoadipamido)-3 beta-hydroxy-3 alpha-methylcepham-4 alpha-carboxylic acid, a new metabolite from Cephalosporium acremonium fermentation

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Isolation and nature of intracellular peptides from a cephalosporin C-producing Cephalosporium sp

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Conversion of 17O/18O labelled δ-(L-α-aminoadlpyl)-L-cysteinyl-D-valine to 17O/18O labelled isopenicillin n in a cell-free extract of . A study by 17O-NMR spectroscopy and mass spectrometry

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Purification of isopenicillin N synthetase

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