Identification of Secretory Granule Phosphatidylinositol 4,5-Bisphosphate-interacting Proteins Using an Affinity Pulldown Strategy (Q58120702)

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Tristan P. Wallis

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Jose L. Jimenez

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Jeffrey J. Gorman

Molecular & Cellular Proteomics

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publication date

20 April 2007

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published in

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volume

6

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issue

7

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page(s)

1158-1169

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cites work

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A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

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Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells

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Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis

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CAPS Acts at a Prefusion Step in Dense-Core Vesicle Exocytosis as a PIP2 Binding Protein

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CAPS1 regulates catecholamine loading of large dense-core vesicles

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There's more to life than neurotransmission: the regulation of exocytosis by synaptotagmin VII.

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Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release

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Calcium-dependent and -independent hetero-oligomerization in the synaptotagmin family.

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Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor

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Synaptotagmin VII as a plasma membrane Ca(2+) sensor in exocytosis

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Synaptotagmin VII is targeted to dense-core vesicles and regulates their Ca2+ -dependent exocytosis in PC12 cells.

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Impaired membrane resealing and autoimmune myositis in synaptotagmin VII-deficient mice

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Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling

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Synaptotagmin VII regulates Ca(2+)-dependent exocytosis of lysosomes in fibroblasts

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The Exocytosis-regulatory protein synaptotagmin VII mediates cell invasion by Trypanosoma cruzi

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Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes

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A process for controlling intracellular bacterial infections induced by membrane injury

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Molecular regulation of membrane resealing in 3T3 fibroblasts.

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Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis

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Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis

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Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue

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LH3, a "homologue" of the mastadenoviral E1B 55-kDa protein is a structural protein of atadenoviruses

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Comparative analysis of tandem C2 domains from the mammalian synaptotagmin family

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ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

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Anti-alpha-fodrin inhibits secretion from permeabilized chromaffin cells

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A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

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Characterization of the localization and function of NECAP 1 in neurons

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Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells

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Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human

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Functional diversity of C2 domains of synaptotagmin family. Mutational analysis of inositol high polyphosphate binding domain.

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Inositol 1,3,4,5-tetrakisphosphate binding activities of neuronal and non-neuronal synaptotagmins. Identification of conserved amino acid substitutions that abolish inositol 1,3,4,5-tetrakisphosphate binding to synaptotagmins III, V, and X.

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Synaptotagmins form a hierarchy of exocytotic Ca(2+) sensors with distinct Ca(2+) affinities

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Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis

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Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells

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RNA interference-mediated silencing of synaptotagmin IX, but not synaptotagmin I, inhibits dense-core vesicle exocytosis in PC12 cells

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Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I

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Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation.

21 January 2018

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The C2 domains of synaptotagmin--partners in exocytosis

21 January 2018

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Discrete residues in the c(2)b domain of synaptotagmin I independently specify endocytic rate and synaptic vesicle size

21 January 2018

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Synaptotagmin mutants Y311N and K326/327A alter the calcium dependence of neurotransmission

21 January 2018

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Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1.

21 January 2018

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C2B polylysine motif of synaptotagmin facilitates a Ca2+-independent stage of synaptic vesicle priming in vivo.

21 January 2018

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Synaptotagmin interaction with the syntaxin/SNAP-25 dimer is mediated by an evolutionarily conserved motif and is sensitive to inositol hexakisphosphate

21 January 2018

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The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo.

21 January 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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