Alzheimer's disease amyloid precursor protein (ApPP): proteolytic processing, secretases and βA4 amyloid production (Q58266260)

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Differences between vascular and plaque core amyloid in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer's disease and control brain contain soluble derivatives of the amyloid protein precursor that end within the beta amyloid protein region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

"Secretase," Alzheimer amyloid protein precursor secreting enzyme is not sequence-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Beta-amyloid precursor protein cleavage by a membrane-bound protease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Altered cleavage and secretion of a recombinant beta-APP bearing the Swedish familial Alzheimer's disease mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Characterization by radiosequencing of the carboxyl-terminal derivatives produced from normal and mutant amyloid β protein precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Different transforming growth factor-alpha species are derived from a glycosylated and palmitoylated transmembrane precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Differential expression of carboxyl terminal derivatives of amyloid precursor protein among cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Modulation of beta-amyloid precursor protein secretion in differentiated and nondifferentiated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of a cholera toxin sensitive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Activation of the secretory pathway leads to a decrease in the intracellular amyloidogenic fragments generated from the amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Calcium ionophore increases amyloid beta peptide production by cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer's disease amyloid beta-clipping enzyme (APP secretase): identification, purification, and characterization of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Characterization of proteases with the specificity to cleave at the secretase-site of beta-APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The processing of Alzheimer A4/beta-amyloid protein precursor: identification of a human brain metallopeptidase which cleaves -Lys-Leu- in a model peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Two-way cleavage of β-amyloid protein precursor by multicatalytic proteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer amyloid beta/A4 peptide binding sites and a possible 'APP-secretase' activity associated with rat brain cortical membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer β-amyloid protein from its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Identification of a metalloprotease from Alzheimer's disease brain able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of beta-amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Cathepsin G: localization in human cerebral cortex and generation of amyloidogenic fragments from the beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The amino acid sequence of neuritic plaque amyloid from a familial Alzheimer's disease patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Detection of distinct isoform patterns of the beta-amyloid precursor protein in human platelets and lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Evidence for lysosomal processing of amyloid beta-protein precursor in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Overexpression of amyloid precursor protein alters its normal processing and is associated with neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Human neurons derived from a teratocarcinoma cell line express solely the 695-amino acid amyloid precursor protein and produce intracellular beta-amyloid or A4 peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Generation of beta A4 from the amyloid protein precursor and fragments thereof

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Cell biology of neuronal endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

cDNA cloning of porcine brain prolyl endopeptidase and identification of the active-site seryl residue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Membrane-anchored growth factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Aberrant proteolysis of the beta-amyloid precursor protein in familial Alzheimer's disease lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118

A calcium-stimulated serine protease from monkey brain degrades the beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129409146118