Multidrug Efflux Pumps and Cancer Stem Cells: Insights Into Multidrug Resistance and Therapeutic Development (Q58277244)

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Normal stem cells and cancer stem cells: similar and different

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

ABCG2 expression is correlated neither to side population nor to hematopoietic progenitor function in human umbilical cord blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

A distinct "side population" of cells with high drug efflux capacity in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Cancer stem cells in solid tumors: elusive or illusive?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Mechanisms of cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

The 3' untranslated region of the membrane-bound IL-1R accessory protein mRNA confers tissue-specific destabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Relationships between multidrug resistance (MDR) and stem cell markers in human chronic myeloid leukemia cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Novel 5' untranslated region variants of BCRP mRNA are differentially expressed in drug-selected cancer cells and in normal human tissues: implications for drug resistance, tissue-specific expression, and alternative promoter usage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

MicroRNAs play a role in the development of human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Persistence of side population cells with high drug efflux capacity in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Identification of a functional initiator sequence in the human MDR1 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Differential regulation of MDR1 transcription by the p53 family members. Role of the DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multidrug resistant cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Regulation of progenitor cell fusion by ABCB5 P-glycoprotein, a novel human ATP-binding cassette transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Identification of cells initiating human melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

MicroRNA regulation of cancer stem cells and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Structural analogues of smoothened intracellular loops as potent inhibitors of Hedgehog pathway and cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Recent progress on tissue-resident adult stem cell biology and their therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance linked ABCG2 transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14

ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.14