High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice (Q58378937)

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6 December 2019

title

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice (English)

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José Luis De La Pompa Mínguez

6 December 2019

author

2

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6 December 2019

Vuk Stambolic

3

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6 December 2019

author name string

A Suzuki

1

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6 December 2019

A J Elia

4

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6 December 2019

T Sasaki

5

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6 December 2019

I del Barco Barrantes

6

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A Ho

7

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6 December 2019

A Wakeham

8

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6 December 2019

A Itie

9

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W Khoo

10

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6 December 2019

M Fukumoto

11

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T W Mak

12

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6 December 2019

language of work or name

English

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publication date

1 October 1998

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6 December 2019

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6 December 2019

volume

8

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6 December 2019

page(s)

1169-1178

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6 December 2019

issue

21

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

6 December 2019

cites work

1 reference

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7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

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7 January 2021

Analysis of PTEN and the 10q23 region in primary prostate carcinomas

1 reference

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7 January 2021

Inactivation of the PTEN/MMAC1/TEP1 gene in human lung cancers.

1 reference

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7 January 2021

Analysis of the PTEN gene in human meningiomas

1 reference

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7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

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7 January 2021

Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

1 reference

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7 January 2021

PTEN: sometimes taking it off can be better than putting it on.

1 reference

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7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

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7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Thymic lymphoma induction by the AKT8 murine retrovirus

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7 January 2021

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

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7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

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7 January 2021

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation

1 reference

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7 January 2021

The Brachyury gene encodes a novel DNA binding protein

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7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

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7 January 2021

Essential role of Mash-2 in extraembryonic development

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7 January 2021

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse.

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7 January 2021

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

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7 January 2021

Wnt-3a regulates somite and tailbud formation in the mouse embryo

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7 January 2021

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

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7 January 2021

Pten is essential for embryonic development and tumour suppression

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7 January 2021

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation

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7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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7 January 2021

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

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7 January 2021

Expression of a specific mouse germ cell nuclear antigen (GCNA1) by early embryonic testicular teratoma cells in 129/Sv-Sl/+ mice

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7 January 2021

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

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7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

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7 January 2021

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development.

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7 January 2021

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9799734%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference