Evidence that Thrombin-stimulated DNA Synthesis in Pulmonary Arterial Fibroblasts Involves Phosphatidylinositol 3-kinase-dependent p70 Ribosomal S6 Kinase Activation (Q58450348)

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English	Evidence that Thrombin-stimulated DNA Synthesis in Pulmonary Arterial Fibroblasts Involves Phosphatidylinositol 3-kinase-dependent p70 Ribosomal S6 Kinase Activation	article

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scholarly article

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1 November 2019

Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation (English)

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1 November 2019

2

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1 November 2019

4

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1 November 2019

author name string

C M Belham

1

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1 November 2019

D P Twomey

3

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1 November 2019

R M Wadsworth

5

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1 November 2019

R Plevin

6

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1 November 2019

publication date

1 January 1997

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1 November 2019

number of pages

8

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inferred from page(s)

Cellular Signalling

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1 November 2019

9

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1 November 2019

1

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1 November 2019

109-116

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1 November 2019

Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

S6 phosphorylation and the p70s6k/p85s6k

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential subcellular localisation of two isoforms of p70 S6 protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear localization of p85s6k: functional requirement for entry into S phase.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

p70s6k function is essential for G1 progression

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

MAP2 kinase and 70K S6 kinase lie on distinct signalling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple independent inputs are required for activation of the p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and characterization of bovine brain type I phosphatidylinositol kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C regulates the stimulated accumulation of 3-phosphorylated phosphoinositides in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of phosphatidylinositol 3-kinase by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective Inhibition of p70 S6 Kinase Activation by Phosphatidylinositol 3‐Kinase Inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of phosphatidylinositol kinase in PDGF receptor signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal Activation of P70 S6 Kinase by Insulin in Cells Overexpressing Dominant Negative 85-kDa Subunit of Phosphoinositide 3-Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

EGF-induced activation of 70-kDa S6 kinase in CHO cells expressing human EGF receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2896%2900120-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0898-6568(96)00120-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9067639%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9067639%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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