Examining Interactions of HIV-1 Reverse Transcriptase with Single-stranded Template Nucleotides by Nucleoside Analog Interference (Q58462554)

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27 December 2019

title

Examining interactions of HIV-1 reverse transcriptase with single-stranded template nucleotides by nucleoside analog interference (English)

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27 December 2019

1

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27 December 2019

Vinayaka R. Prasad

series ordinal

3

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27 December 2019

author name string

Timothy S Fisher

series ordinal

2

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27 December 2019

Stuart F J Le Grice

series ordinal

4

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27 December 2019

language of work or name

English

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publication date

25 July 2006

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Journal of Biological Chemistry

27 December 2019

published in

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27 December 2019

volume

281

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27 December 2019

issue

38

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27 December 2019

page(s)

27873-27881

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Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

27 December 2019

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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

21 January 2018

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The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1

21 January 2018

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Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution

21 January 2018

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Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms

21 January 2018

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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

21 January 2018

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

21 January 2018

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

21 January 2018

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Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site

21 January 2018

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Alterations to the primer grip of p66 HIV-1 reverse transcriptase and their consequences for template-primer utilization

21 January 2018

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Isolation and characterization of a dideoxyguanosine triphosphate-resistant mutant of human immunodeficiency virus reverse transcriptase

21 January 2018

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Nucleotide insertion and primer extension at abasic template sites in different sequence contexts.

21 January 2018

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Differential tolerance to DNA polymerization by HIV-1 reverse transcriptase on N6 adenine C10R and C10S benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide-adducted templates

21 January 2018

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Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand

21 January 2018

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Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection

21 January 2018

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Two modes of HIV-1 polypurine tract cleavage are affected by introducing locked nucleic acid analogs into the (-) DNA template.

21 January 2018

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Interaction of the Ty3 reverse transcriptase thumb subdomain with template-primer

21 January 2018

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Investigating HIV-1 polypurine tract geometry via targeted insertion of abasic lesions in the (-)-DNA template and (+)-RNA primer

21 January 2018

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A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis

21 January 2018

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Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.

21 January 2018

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Mutations in the RNase H primer grip domain of murine leukemia virus reverse transcriptase decrease efficiency and accuracy of plus-strand DNA transfer

21 January 2018

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An expanded model of replicating human immunodeficiency virus reverse transcriptase

21 January 2018

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Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer

21 January 2018

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Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase

21 January 2018

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Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis

21 January 2018

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Nonpolar thymine isosteres in the Ty3 polypurine tract DNA template modulate processing and provide a model for its recognition by Ty3 reverse transcriptase

21 January 2018

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Examining Ty3 polypurine tract structure and function by nucleoside analog interference.

21 January 2018

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DNA-thumb interactions and processivity of T7 DNA polymerase in comparison to yeast polymerase eta.

21 January 2018

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Identification of specific nonbridging phosphate oxygens important for DNA cleavage by human topoisomerase I.

21 January 2018

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Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformation

21 January 2018

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Snapshots of replication through an abasic lesion; structural basis for base substitutions and frameshifts

21 January 2018

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21 January 2018

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Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase

21 January 2018

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Modeling of Flap Endonuclease Interactions with DNA Substrate

21 January 2018

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Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

21 January 2018

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Inhibition of the initiation of HIV-1 reverse transcription by 3'-azido-3'-deoxythymidine. Comparison with elongation

21 January 2018

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Direct and indirect contributions of RNA secondary structure elements to the initiation of HIV-1 reverse transcription

21 January 2018

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The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M603970200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867979%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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