Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies (Q58617548)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Nidhi Sahni

10

1 reference

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1 May 2020

Gordon B. Mills

12

1 reference

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1 May 2020

author name string

Patrick K S Ng

2

1 reference

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1 May 2020

Kang Jin Jeong

3

1 reference

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1 May 2020

S H Shao

4

1 reference

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1 May 2020

Zhenlin Ju

5

1 reference

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1 May 2020

P G Leonard

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Xu Hua

7

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1 May 2020

Christopher P Vellano

8

1 reference

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1 May 2020

Richard Woessner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Kenneth L Scott

11

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1 May 2020

language of work or name

English

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publication date

2 November 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

published in

Nature Communications

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1 May 2020

volume

9

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1 May 2020

issue

1

1 reference

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1 May 2020

page(s)

4583

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Systematic Functional Annotation of Somatic Mutations in Cancer.

1 May 2020

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Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors

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30 November 2018

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Oncogenic Kit signals on endolysosomes and endoplasmic reticulum are essential for neoplastic mast cell proliferation

30 November 2018

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The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.

30 November 2018

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A general framework for estimating the relative pathogenicity of human genetic variants

30 November 2018

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Rare EGFR exon 18 and exon 20 mutations in non-small-cell lung cancer on 10 117 patients: a multicentre observational study by the French ERMETIC-IFCT network

30 November 2018

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Large-scale analysis of PDGFRA mutations in melanomas and evaluation of their sensitivity to tyrosine kinase inhibitors imatinib and crenolanib

30 November 2018

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Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

30 November 2018

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PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations

30 November 2018

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Activating somatic FGFR2 mutations in breast cancer

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Prevalence, clinico-pathological value, and co-occurrence of PDGFRA abnormalities in diffuse gliomas

30 November 2018

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Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors

30 November 2018

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Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma

30 November 2018

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30 November 2018

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Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

30 November 2018

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30 November 2018

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PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

30 November 2018

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30 November 2018

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30 November 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

30 November 2018

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30 November 2018

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Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors

30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

30 November 2018

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30 November 2018

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Homodimerization and constitutive activation of the erythropoietin receptor

30 November 2018

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Prognostic value of KIT/PDGFRA mutations in gastrointestinal stromal tumours (GIST): Polish Clinical GIST Registry experience

30 November 2018

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Crossref

https://api.crossref.org/works/10.1038%2FS41467-018-06949-W

inferred from DOI database lookup

7 January 2021

based on heuristic

The bittersweet promise of glycobiology

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https://api.crossref.org/works/10.1038%2FS41467-018-06949-W

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41467-018-06949-W

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30389923%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30389923

1 reference