PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients (Q58813317)

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Andrea Lampis

2

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Maria Di Bartolomeo

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Lucio Bertario

11

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Marco A. Pierotti

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author name string

M Orsenigo

3

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A Gevorgyan

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M Losa

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M Frattini

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C Riva

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S Andreola

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E Bajetta

10

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E Leo

12

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S Pilotti

14

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publication date

22 July 2008

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published in

Annals of Oncology

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volume

20

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issue

1

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page(s)

84-90

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Cetuximab for the treatment of colorectal cancer.

19 May 2020

cites work

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PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients

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KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

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KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab

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Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

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Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

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Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

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CDX2Polymorphisms, RNA Expression, and Risk of Colorectal Cancer

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A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma

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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

21 January 2018

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High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

21 January 2018

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Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points

21 January 2018

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Epidermal growth factor receptor inhibitors in colorectal cancer treatment: what's new?

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Mutations of the BRAF gene in human cancer

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24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE00766

Identifiers

DOI

10.1093/ANNONC/MDN541

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18669866%20AND%20SRC:MED&resulttype=core&format=json

19 May 2020

1 reference