Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56 lck (Q59025223)

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16 September 2019

title

Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck (English)

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16 September 2019

1

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16 September 2019

4

Veillette A

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16 September 2019

author name string

Miceli MC

series ordinal

2

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16 September 2019

Parnes JR

series ordinal

3

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16 September 2019

language of work or name

English

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publication date

1 March 1991

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16 September 2019

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16 September 2019

volume

350

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16 September 2019

issue

6313

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16 September 2019

page(s)

62-66

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https://scigraph.springernature.com/pub.10.1038/350062a0

16 September 2019

exact match

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cites work

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes

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7 January 2021

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

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7 January 2021

Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes

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7 January 2021

Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

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7 January 2021

Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

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7 January 2021

A signaling role for the cytoplasmic segment of the CD8 alpha chain detected under limiting stimulatory conditions.

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7 January 2021

Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity

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7 January 2021

Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts

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7 January 2021

Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)

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7 January 2021

Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation

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7 January 2021

Insulin-specific T cell hybridomas derived from (H-2b x H-2k)F1 mice preferably employ F1-unique restriction elements for antigen recognition

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7 January 2021

Acquisition of an additional antigen specificity after mouse CD4 gene transfer into a T helper hybridoma

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7 January 2021

Role of CD4 and CD8 in enhancing T-cell responses to antigen

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7 January 2021

T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

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7 January 2021

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

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7 January 2021

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

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7 January 2021

CD4 and CD8 molecules can physically associate with the same T-cell receptor

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7 January 2021

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

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7 January 2021

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

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7 January 2021

Changes in the relative abundance of type I and type II lck mRNA transcripts suggest differential promoter usage during T-cell development

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7 January 2021

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

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7 January 2021

p56lck protein-tyrosine kinase is cytoskeletal and does not bind to polyomavirus middle T antigen

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7 January 2021

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

7 January 2021

The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function

1 reference

7 January 2021

Identification of a monoclonal antibody specific for a murine T3 polypeptide

1 reference

7 January 2021

T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4

1 reference

7 January 2021

Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

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7 January 2021

Identifiers

DOI

10.1038/350062A0

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1706070%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 September 2019

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