Monoclonal antibodies inhibit prion replication and delay the development of prion disease (Q59053964)

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1 November 2019

title

Monoclonal antibodies inhibit prion replication and delay the development of prion disease (English)

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1 November 2019

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1

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1 November 2019

Mourad Tayebi

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1 November 2019

8

John Collinge

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1 November 2019

author name string

Perry Enever

2

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1 November 2019

Rosey Mushens

4

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1 November 2019

Jackie Linehan

5

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1 November 2019

Sebastian Brandner

6

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1 November 2019

David Anstee

7

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1 November 2019

Simon Hawke

9

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1 November 2019

language of work or name

English

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publication date

1 March 2003

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1 November 2019

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1 November 2019

volume

422

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1 November 2019

page(s)

80-83

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1 November 2019

issue

6927

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https://scigraph.springernature.com/pub.10.1038/nature01457

1 November 2019

exact match

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cites work

Multiple folding pathways for heterologously expressed human prion protein

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Immunization delays the onset of prion disease in mice.

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Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane

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Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

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7 January 2021

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

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7 January 2021

The same prion strain causes vCJD and BSE

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7 January 2021

A new variant of Creutzfeldt-Jakob disease in the UK.

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7 January 2021

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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

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7 January 2021

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

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7 January 2021

Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations.

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7 January 2021

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

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7 January 2021

Regional heterogeneity of cellular prion protein isoforms in the mouse brain

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7 January 2021

Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent

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7 January 2021

Modulation of proteinase-K resistant prion protein by prion peptide immunization.

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7 January 2021

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

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7 January 2021

Mammalian prion proteins: enigma, variation and vaccination

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7 January 2021

PrP expression in B lymphocytes is not required for prion neuroinvasion

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7 January 2021

Impaired prion replication in spleens of mice lacking functional follicular dendritic cells

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7 January 2021

Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

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7 January 2021

Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies

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7 January 2021

Postexposure prophylaxis against prion disease with a stimulator of innate immunity

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7 January 2021

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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7 January 2021

Normal host prion protein necessary for scrapie-induced neurotoxicity.

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7 January 2021

Identification of a gene which controls the incubation period of some strains of scrapie agent in mice.

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7 January 2021

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

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7 January 2021