Localization of pre-mRNA splicing in mammalian nuclei (Q59083697)

1

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Krishan L. Taneja

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Robert H. Singer

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Michael R. Green

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G Zhang

1

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K L Taneja

2

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R H Singer

3

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M R Green

https://scigraph.springernature.com/pub.10.1038/372809a0

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language of work or name

English

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publication date

December 1994

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published in

Nature

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volume

372

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issue

6508

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page(s)

809-812

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809-12

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exact match

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cites work

Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles

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Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

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Macromolecular domains within the cell nucleus

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Nuclear RNA tracks: structural basis for transcription and splicing?

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RNA travel: tracks from DNA to cytoplasm

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Discrete nuclear domains of poly(A) RNA and their relationship to the functional organization of the nucleus

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Associations between distinct pre-mRNA splicing components and the cell nucleus

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Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors

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Higher level organization of individual gene transcription and RNA splicing

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Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes

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Splice site selection, rate of splicing, and alternative splicing on nascent transcripts

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Small nuclear ribonucleoproteins and heterogeneous nuclear ribonucleoproteins in the amphibian germinal vesicle: loops, spheres, and snurposomes

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Splicing precedes polyadenylation during Drosophila E74A transcription

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Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription.

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Directing cell division during development

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Progression of the cell cycle through mitosis leads to abortion of nascent transcripts

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Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

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The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.

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Nuclear organization of splicing small nuclear ribonucleoproteins in adenovirus-infected cells.

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Fluorescent labeling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus

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Visualization of focal sites of transcription within human nuclei.

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Ultrastructural distribution of nuclear ribonucleoproteins as visualized by immunocytochemistry on thin sections

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In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism

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Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans

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Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

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Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy

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