Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis (Q59243333)

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28 October 2019

title

Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis (English)

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28 October 2019

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2

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28 October 2019

5

Sandlie I

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28 October 2019

author name string

Brekke OH

series ordinal

1

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28 October 2019

Aase A

series ordinal

3

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28 October 2019

Sandin RH

series ordinal

4

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28 October 2019

language of work or name

English

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publication date

1 October 1994

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European Journal of Immunology

28 October 2019

published in

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28 October 2019

volume

24

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28 October 2019

issue

10

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28 October 2019

page(s)

2542-2547

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The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fc gamma receptors, but the heavy chains must be disulfide bonded

28 October 2019

cites work

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7 January 2021

The binding site for C1q on IgG

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7 January 2021

Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins

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7 January 2021

Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hinge

1 reference

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7 January 2021

Activation of complement by an IgG molecule without a genetic hinge

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7 January 2021

The differential ability of human IgG1 and IgG4 to activate complement is determined by the COOH-terminal sequence of the CH2 domain

1 reference

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7 January 2021

The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830241042

7 January 2021

Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation

1 reference

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7 January 2021

Localization of the binding site for the human high-affinity Fc receptor on IgG.

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7 January 2021

Molecular definition of interaction sites on human IgG for Fc receptors (huFc gamma R)

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7 January 2021

Multiple binding sites on the CH2 domain of IgG for mouse Fc gamma R11.

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7 January 2021

Molecular recognition of antibody (IgG) by cellular Fc receptor (FcRI)

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7 January 2021

Rapid and efficient site-specific mutagenesis without phenotypic selection

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7 January 2021

DNA sequencing with chain-terminating inhibitors

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7 January 2021

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

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7 January 2021

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation

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7 January 2021

C1q binding to chimeric monoclonal IgG3 antibodies consisting of mouse variable regions and human constant regions with shortened hinge containing 15 to 47 amino acids

1 reference

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7 January 2021

Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons

1 reference

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7 January 2021

The use of a hapten-Fab conjugate to sensitize target cells for antibody-dependent complement-mediated lysis and antibody-dependent cell-mediated cytotoxicity

1 reference

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7 January 2021

A protein structural change in aglycosylated IgG3 correlates with loss of huFc gamma R1 and huFc gamma R111 binding and/or activation

1 reference

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7 January 2021

Human IgG subclass pattern of inducing complement-mediated cytolysis depends on antigen concentration and to a lesser extent on epitope patchiness, antibody affinity and complement concentration

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7 January 2021

Immunoglobulin G: functional sites

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7 January 2021

Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers

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7 January 2021

Natural infection of man with group A streptococci. Levels; restriction in class, subclass, and type; and clonal appearance of polysaccharide-group-specific antibodies

1 reference

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7 January 2021

Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution

1 reference

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830241042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925582%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

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