A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus (Q59354857)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30092199%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

title

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus (English)

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16 April 2020

main subject

Orthoebolavirus zairense

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14

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James E. Crowe, Jr.

19

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John M Dye

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Kristian G Andersen

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Yoshihiro Kawaoka

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Erica Ollmann Saphire

25

object named as

Erica Ollmann Saphire

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Gary P Kobinger

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1

Bronwyn M Gunn

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Galit Alter

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Douglas A. Lauffenburger

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object named as

Douglas Lauffenburger

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12

Xiangguo Qiu

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Kartik Chandran

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7

Peter J Halfmann

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author name string

Wen-Han Yu

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Marcus M Karim

3

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Jennifer M Brannan

4

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Andrew S Herbert

5

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Anna Z Wec

6

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Sharon L Schendel

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Karthik Gangavarapu

10

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Tyler Krause

11

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Shinhua He

13

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Todd J Suscovich

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Jonathan Lai

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Larry Zeitlin

18

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Marnie L Fusco

8

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language of work or name

English

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publication date

1 August 2018

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16 April 2020

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volume

24

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issue

2

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page(s)

221-233.e5

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describes a project that uses

16 April 2020

Cytoscape

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9 June 2022

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inferred from PubMed Central ID database lookup

cites work

The molecular dissection of Fc gamma receptor mediated phagocytosis

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12 December 2020

A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

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12 December 2020

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

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Epitopes involved in antibody-mediated protection from Ebola virus

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12 December 2020

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

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Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody

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CD107a as a functional marker for the identification of natural killer cell activity.

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Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys

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12 December 2020

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

1 reference

12 December 2020

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

1 reference

12 December 2020

Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

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12 December 2020

Monoclonal antibodies for cancer immunotherapy

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Immunoglobulin G in Ebola outbreak survivors, Gabon

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12 December 2020

Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant

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Properties of mouse and human IgG receptors and their contribution to disease models

1 reference

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Crosstalk between human IgG isotypes and murine effector cells

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12 December 2020

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

1 reference

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Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b

1 reference

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Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail

1 reference

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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

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Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity

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12 December 2020

Type I and type II Fc receptors regulate innate and adaptive immunity

1 reference

12 December 2020

Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function

1 reference

12 December 2020

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

1 reference

12 December 2020

Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity

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12 December 2020

Ebola vaccine--an urgent international priority

1 reference

12 December 2020

A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis

1 reference

12 December 2020

A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report

1 reference

12 December 2020

Differential Fc-Receptor Engagement Drives an Anti-tumor Vaccinal Effect

1 reference

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Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

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Broadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protection

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Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection

1 reference

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Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak

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Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody

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Two-mAb cocktail protects macaques against the Makona variant of Ebola virus

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A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

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Modulating Antibody Functionality in Infectious Disease and Vaccination

1 reference

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Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans.

1 reference

12 December 2020

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses.

1 reference

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Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability.

1 reference

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Glycosylation engineering of therapeutic IgG antibodies: challenges for the safety, functionality and efficacy.

1 reference

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Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design

1 reference

12 December 2020

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

1 reference

12 December 2020

10.1016/J.CHOM.2018.07.009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30092199%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

1 reference

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16 April 2020

PubMed publication ID

30092199

1 reference