A Semi-mechanistic Modeling Strategy to Link In Vitro and In Vivo Drug Release for Modified Release Formulations (Q59521850)

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13 February 2020

title

A semi-mechanistic modeling strategy to link in vitro and in vivo drug release for modified release formulations (English)

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13 February 2020

1

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13 February 2020

Werner Weitschies

series ordinal

4

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13 February 2020

5

Mats O Karlsson

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13 February 2020

author name string

Erik Söderlind

series ordinal

2

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13 February 2020

Ulf G Eriksson

series ordinal

3

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publication date

27 September 2011

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13 February 2020

published in

Pharmaceutical Research

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volume

29

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issue

3

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page(s)

695-706

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Transit of pharmaceutical dosage forms through the small intestine

13 February 2020

cites work

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12 December 2020

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Population in vitro-in vivo correlation model for pramipexole slow-release oral formulations

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Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutions

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Comparison of dissolution profiles obtained from nifedipine extended release once a day products using different dissolution test apparatuses.

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12 December 2020

Prediction of modified release pharmacokinetics and pharmacodynamics from in vitro, immediate release, and intravenous data

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12 December 2020

Single-dose pharmacokinetics, pharmacodynamics and safety of AZD0837, a novel oral direct thrombin inhibitor, in young healthy male subjects.

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Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses

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A novel in vitro and numerical analysis of shear-induced drug release from extended-release tablets in the fed stomach.

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Regional postprandial differences in pH within the stomach and gastroesophageal junction

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Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling

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Application of gastrointestinal simulation for extensions for biowaivers of highly permeable compounds

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Predicting in vivo absorption behavior of oral modified release dosage forms containing pH-dependent poorly soluble drugs using a novel pH-adjusted biphasic in vitro dissolution test.

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Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update

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Modeling and comparison of dissolution profiles

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Prediction-corrected visual predictive checks for diagnosing nonlinear mixed-effects models

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Draft guidance for industry extended-release solid oral dosage forms. Development, evaluation and application of in vitro-in vivo correlations

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The transit of dosage forms through the small intestine

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Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form

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Population-based mechanistic prediction of oral drug absorption

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Diagnosing model diagnostics

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Handling data below the limit of quantification in mixed effect models

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12 December 2020

Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs

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Perl-speaks-NONMEM (PsN)--a Perl module for NONMEM related programming

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Whole-body physiologically based pharmacokinetic population modelling of oral drug administration: inter-individual variability of cimetidine absorption

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Ways to fit a PK model with some data below the quantification limit

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Mechanism-based prediction of particle size-dependent dissolution and absorption: cilostazol pharmacokinetics in dogs.

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12 December 2020

Magnetic marker monitoring: high resolution real-time tracking of oral solid dosage forms in the gastrointestinal tract.

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12 December 2020

Does warfarin for stroke thromboprophylaxis protect against MI in atrial fibrillation patients?

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12 December 2020

Mechanistic modeling of a magnetic marker monitoring study linking gastrointestinal tablet transit, in vivo drug release, and pharmacokinetics.

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12 December 2020

Determination of the disintegration behavior of magnetically marked tablets

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12 December 2020

10.1007/S11095-011-0594-3

Identifiers

DOI

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13 February 2020

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