Transduction of Full-length Dystrophin to Multiple Skeletal Muscles Improves Motor Performance and Life Span in Utrophin/Dystrophin Double Knockout Mice (Q59876164)

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Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and life span in utrophin/dystrophin double knockout mice

Language	Label	Description	Also known as
English	Transduction of Full-length Dystrophin to Multiple Skeletal Muscles Improves Motor Performance and Life Span in Utrophin/Dystrophin Double Knockout Mice	No description defined	Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and life span in utrophin/dystrophin double knockout mice

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scholarly article

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Transduction of Full-length Dystrophin to Multiple Skeletal Muscles Improves Motor Performance and Life Span in Utrophin/Dystrophin Double Knockout Mice (English)

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Transduction of full-length dystrophin to multiple skeletal muscles improves motor performance and life span in utrophin/dystrophin double knockout mice (English)

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object named as

En Kimura

5

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author name string

Ryoko Kawano

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Masatoshi Ishizaki

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Yasushi Maeda

3

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Yuji Uchida

4

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Makoto Uchino

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En Kimura

5

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language of work or name

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publication date

May 2008

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Molecular Therapy

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16

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5

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825-831

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825-31

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Population frequencies of inherited neuromuscular diseases—A world survey

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Dystrophin: the protein product of the Duchenne muscular dystrophy locus

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Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy

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Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy

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Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice

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Subtle neuromuscular defects in utrophin-deficient mice

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Cre/loxP-mediated adenovirus type 5 packaging signal excision demonstrates that core element VI is sufficient for virus packaging

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A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase

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Effective repetitive dystrophin gene transfer into skeletal muscle of adult mdx mice using a helper-dependent adenovirus vector expressing the coxsackievirus and adenovirus receptor (CAR) and dystrophin

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Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin

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Improved performance of a fully gutted adenovirus vector containing two full-length dystrophin cDNAs regulated by a strong promoter

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rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.

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Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

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AAV vector-mediated microdystrophin expression in a relatively small percentage of mdx myofibers improved the mdx phenotype

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Stable transduction of myogenic cells with lentiviral vectors expressing a minidystrophin

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Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene

1 reference

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Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

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Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice

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Immune response to full-length dystrophin delivered to Dmd muscle by a high-capacity adenoviral vector

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Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy

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Neuronal nitric oxide synthase and dystrophin-deficient muscular dystrophy

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Impaired metabolic modulation of alpha-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

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Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

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C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice

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Helper (CD4(+)) and cytotoxic (CD8(+)) T cells promote the pathology of dystrophin-deficient muscle

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10.1038/MT.2008.23

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