Evaluation of the prognostic value of all four HER family receptors in patients with metastatic breast cancer treated with trastuzumab: A Hellenic Cooperative Oncology Group (HeCOG) study (Q60046313)

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scientific article published in PLoS ONE

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English	Evaluation of the prognostic value of all four HER family receptors in patients with metastatic breast cancer treated with trastuzumab: A Hellenic Cooperative Oncology Group (HeCOG) study	scientific article published in PLoS ONE

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12 April 2020

Evaluation of the prognostic value of all four HER family receptors in patients with metastatic breast cancer treated with trastuzumab: A Hellenic Cooperative Oncology Group (HeCOG) study (English)

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12 April 2020

metastatic breast cancer

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based on heuristic

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Angelos Koutras

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12 April 2020

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12 April 2020

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Georgios Lazaridis

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12 April 2020

Georgia-Angeliki Koliou

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12 April 2020

George Kouvatseas

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12 April 2020

Christos Christodoulou

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12 April 2020

Dimitrios Pectasides

6

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12 April 2020

Vassiliki Kotoula

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12 April 2020

Anna Batistatou

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12 April 2020

Mattheos Bobos

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12 April 2020

Eleftheria Tsolaki

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12 April 2020

Kyriaki Papadopoulou

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12 April 2020

George Pentheroudakis

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12 April 2020

Pavlos Papakostas

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12 April 2020

Stavroula Pervana

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12 April 2020

Kalliopi Petraki

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12 April 2020

Evangelia Razis

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12 April 2020

Amanda Psyrri

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12 April 2020

Dimitrios Bafaloukos

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12 April 2020

Konstantine T Kalogeras

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12 April 2020

Haralambos P Kalofonos

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12 April 2020

George Fountzilas

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12 April 2020

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6 December 2018

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12 April 2020

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12 April 2020

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12 April 2020

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12 April 2020

e0207707

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12 April 2020

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Creative Commons Attribution 4.0 International

6 December 2018

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April 2022 Public Data File from Crossref

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0 references

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-erbB-3 protein expression in human breast cancer: comparison with other tumour variables and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1029 patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-erbB-3: a nuclear protein in mammary epithelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-world performance of HER2 testing--National Surgical Adjuvant Breast and Bowel Project experience

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concordance between local and central laboratory HER2 testing in the breast intergroup trial N9831

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical evaluation of HER-2 status: which test to use?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of ERBB family mRNA expression in breast carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time quantitative PCR of microdissected paraffin-embedded breast carcinoma: an alternative method for HER-2/neu analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic growth factor receptors: implications for signal transduction therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reporting recommendations for tumor marker prognostic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlated expression of erbB-3 with hormone receptor expression and favorable clinical outcome in invasive ductal carcinomas of the breast

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the prognostic and predictive value of HER-1/EGFR in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER2 status and benefit from adjuvant trastuzumab in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR, pMAPK, pAkt and PTEN status by immunohistochemistry: correlation with clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The upgraded role of HER3 and HER4 receptors in breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of HER4 associates with increased sensitivity to Herceptin in patients with metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fifteen-year trends in metastatic breast cancer survival in Greece

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of RT-PCR in formalin-fixed and paraffin-embedded lung cancer tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical expression of HER1, HER3, and HER4 in HER2-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of gene expression profiling by reverse transcription quantitative PCR between fresh frozen and formalin-fixed, paraffin-embedded breast cancer tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Automated extraction of DNA and RNA from a single formalin-fixed paraffin-embedded tissue section for analysis of both single-nucleotide polymorphisms and mRNA expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of topoisomerase II-alpha gene in human breast cancer: association with responsiveness to anthracycline-based chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-negative phenotype is of adverse prognostic value in patients treated with dose-dense sequential adjuvant chemotherapy: a translational research analysis in the context of a Hellenic Cooperative Oncology Group (HeCOG) randomized phase III tri

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic and acquired resistance to HER2-targeted therapies in HER2 gene-amplified breast cancer: mechanisms and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER-3 status by immunohistochemistry in HER-2-positive metastatic breast cancer patients treated with trastuzumab: correlation with clinical outcome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topoisomerase II alpha gene amplification is a favorable prognostic factor in patients with HER2-positive metastatic breast cancer treated with trastuzumab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-expression of receptors of the HER family correlates with clinical outcome in non-small cell lung cancer (NSCLC).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ quantitative measurement of HER2mRNA predicts benefit from trastuzumab-containing chemotherapy in a cohort of metastatic breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p85 protein expression is associated with poor survival in HER2-positive patients with advanced breast cancer treated with trastuzumab.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR expression is associated with decreased benefit from trastuzumab in the NCCTG N9831 (Alliance) trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAI-1 and HER2 interaction in advanced breast cancer disease: evidence for added benefit from trastuzumab in HER2-negative patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the prognostic significance of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) validation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MYC copy gain, chromosomal instability and PI3K activation as potential markers of unfavourable outcome in trastuzumab-treated patients with metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the Prognostic Value of RANK, OPG, and RANKL mRNA Expression in Early Breast Cancer Patients Treated with Anthracycline-Based Adjuvant Chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30521571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0207707

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12 April 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30521571%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30521571%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

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