Solution structure of the cyclosporin A/cyclophilin complex by NMR (Q60063832)

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12 October 2019

title

Solution structure of the cyclosporin A/cyclophilin complex by NMR (English)

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12 October 2019

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Thériault Y

1

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12 October 2019

Logan TM

2

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12 October 2019

Meadows R

3

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12 October 2019

Yu L

4

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12 October 2019

Olejniczak ET

5

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12 October 2019

Holzman TF

6

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12 October 2019

Simmer RL

7

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12 October 2019

Fesik SW

8

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12 October 2019

language of work or name

English

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publication date

1 January 1993

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12 October 2019

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12 October 2019

volume

361

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12 October 2019

issue

6407

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12 October 2019

page(s)

88-91

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Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

12 October 2019

cites work

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7 January 2021

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1 reference

7 January 2021

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

1 reference

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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7 January 2021

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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7 January 2021

Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution

1 reference

7 January 2021

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

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7 January 2021

The X-ray structure of a tetrapeptide bound to the active site of human cyclophilin A

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7 January 2021

The NMR structure of cyclosporin A bound to cyclophilin in aqueous solution

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7 January 2021

NMR studies of [U-13C]cyclosporin A bound to cyclophilin: bound conformation and portions of cyclosporin involved in binding

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7 January 2021

The mechanism of action of cyclosporin A and FK506

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7 January 2021

Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data

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7 January 2021

Molecular modeling studies in the complex between cyclophilin and cyclosporin A

1 reference

7 January 2021

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

1 reference

7 January 2021

Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity

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7 January 2021

Determination of three-dimensional structures of proteins from interproton distance data by hybrid distance geometry-dynamical simulated annealing calculations

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7 January 2021

Protein secondary structure determination by NMR. Application with recombinant human cyclophilin.

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7 January 2021

Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin

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7 January 2021

A conformation of cyclosporin A in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex

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7 January 2021

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

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7 January 2021

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

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7 January 2021

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

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7 January 2021

Sampling and efficiency of metric matrix distance geometry: a novel partial metrization algorithm.

1 reference

7 January 2021

1H, 13C and 15N backbone assignments of cyclophilin when bound to cyclosporin A (CsA) and preliminary structural characterization of the CsA binding site

1 reference

7 January 2021

Stereospecific nuclear magnetic resonance assignments of the methyl groups of valine and leucine in the DNA-binding domain of the 434 repressor by biosynthetically directed fractional 13C labeling

1 reference

7 January 2021