Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth (Q60539339)

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29 December 2019

title

Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth (English)

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5

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29 December 2019

author name string

Sara Roos

1

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29 December 2019

Nina Jansson

2

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Isabelle Palmberg

3

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Karin Säljö

4

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Thomas Jansson

6

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language of work or name

English

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publication date

26 April 2007

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29 December 2019

published in

Journal of Physiology

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volume

582

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issue

Pt 1

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page(s)

449-459

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Intrauterine growth curves based on ultrasonically estimated foetal weights.

29 December 2019

cites work

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12 December 2020

Non-human primate fetal kidney transcriptome analysis indicates mammalian target of rapamycin (mTOR) is a central nutrient-responsive pathway.

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12 December 2020

Association between the activity of the system A amino acid transporter in the microvillous plasma membrane of the human placenta and severity of fetal compromise in intrauterine growth restriction

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12 December 2020

Pregnancy outcomes in women with gestational diabetes compared with the general obstetric population

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12 December 2020

Intrauterine growth restriction is associated with a reduced activity of placental taurine transporters

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12 December 2020

Placental transport of leucine and lysine is reduced in intrauterine growth restriction

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12 December 2020

Placental glucose transport and GLUT 1 expression in insulin-dependent diabetes

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12 December 2020

Current concepts in intrauterine growth restriction

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Restraining PI3K: mTOR signalling goes back to the membrane.

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12 December 2020

Maternal and fetal amino acid concentrations in normal pregnancies and in pregnancies with gestational diabetes mellitus

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12 December 2020

Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling

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12 December 2020

Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin

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12 December 2020

Na(+)-K(+)-ATPase is distributed to microvillous and basal membrane of the syncytiotrophoblast in human placenta

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12 December 2020

Placental nutrient transfer and fetal growth

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12 December 2020

L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-re

1 reference

12 December 2020

Placental glucose transport in gestational diabetes mellitus

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12 December 2020

Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies

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12 December 2020

Expression and regulation of 4F2hc and hLAT1 in human trophoblasts

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12 December 2020

Intrauterine growth restriction.

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12 December 2020

Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction

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12 December 2020

Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes

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12 December 2020

Placental-specific IGF-II is a major modulator of placental and fetal growth.

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12 December 2020

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

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Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

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12 December 2020

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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12 December 2020

Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts

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Tor signalling in bugs, brain and brawn

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12 December 2020

Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments.

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12 December 2020

Abnormal Glucose Tolerance During Pregnancy in Pima Indian Women: Long-Term Effects on Offspring

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12 December 2020

Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line

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12 December 2020

Amino acid (system A) transporter activity in microvillous membrane vesicles from the placentas of appropriate and small for gestational age babies

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12 December 2020

Regulatory and molecular aspects of mammalian amino acid transport

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12 December 2020

Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells

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12 December 2020

The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease

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12 December 2020

Idiopathic fetal growth restriction: a pathophysiologic approach

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12 December 2020

Platelet-derived growth factor stimulates LAT1 gene expression in vascular smooth muscle: role in cell growth

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12 December 2020

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

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12 December 2020

Upstream and downstream of mTOR

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12 December 2020

Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation

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12 December 2020

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Umbilical amino acid concentrations in normal and growth-retarded fetuses sampled in utero by cordocentesis

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12 December 2020

Signalling pathways regulating the invasive differentiation of human trophoblasts: a review

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12 December 2020

mTOR: a placental growth signaling sensor

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12 December 2020

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12 December 2020

TOR signaling in growth and metabolism

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12 December 2020

IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review

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12 December 2020

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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12 December 2020

Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet

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12 December 2020

Fetal and maternal plasma insulin-like growth factors and binding proteins in pregnancies with appropriate or retarded fetal growth

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12 December 2020

10.1113/JPHYSIOL.2007.129676

Identifiers

DOI

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29 December 2019

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