Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain (Q60603639)

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scientific article published on 01 July 1999

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English	Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain	scientific article published on 01 July 1999

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10 December 2019

Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain (English)

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10 December 2019

phosphorylation

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Eva-Maria Mandelkow

4

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E M Mandelkow

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R Godemann

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10 December 2019

J Biernat

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10 December 2019

E Mandelkow

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10 December 2019

E M Mandelkow

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10 December 2019

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1 July 1999

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10 December 2019

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10 December 2019

454

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10 December 2019

1-2

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10 December 2019

157-164

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10 December 2019

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

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21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

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21 January 2018

The development of cell processes induced by tau protein requires phosphorylation of serine 262 and 356 in the repeat domain and is inhibited by phosphorylation in the proline-rich domains

1 reference

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21 January 2018

Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain

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21 January 2018

Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3beta transgenes.

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21 January 2018

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

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PDK1, one of the missing links in insulin signal transduction?

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21 January 2018

Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262

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MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

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21 January 2018

Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease

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21 January 2018

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

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21 January 2018

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

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21 January 2018

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

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21 January 2018

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain

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21 January 2018

1 Protein kinase classification

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21 January 2018

The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease

1 reference

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21 January 2018

Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

1 reference

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21 January 2018

Protein phosphatase 1 is targeted to microtubules by the microtubule-associated protein Tau.

1 reference

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21 January 2018

Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356.

1 reference

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21 January 2018

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

1 reference

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21 January 2018

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

1 reference

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21 January 2018

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

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21 January 2018

Glycogen synthase kinase 3 phosphorylates recombinant human tau protein at serine-262 in the presence of heparin (or tubulin)

1 reference

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21 January 2018

Glycogen synthase kinase 3 phosphorylation of different residues in the presence of different factors: analysis on tau protein.

1 reference

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21 January 2018

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

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21 January 2018

Tyrosine dephosphorylation of glycogen synthase kinase-3 is involved in its extracellular signal-dependent inactivation

1 reference

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21 January 2018

Phosphorylation by neuronal cdc2-like protein kinase promotes dimerization of Tau protein in vitro

1 reference

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21 January 2018

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

1 reference

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21 January 2018

Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5.

1 reference

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21 January 2018

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

1 reference

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21 January 2018

Modulation of GSK-3-catalyzed phosphorylation of microtubule-associated protein tau by non-proline-dependent protein kinases.

1 reference

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21 January 2018

Calcium/calmodulin-dependent protein kinase II phosphorylates tau at Ser-262 but only partially inhibits its binding to microtubules

1 reference

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21 January 2018

Tau protein kinase I/GSK-3 beta/kinase FA in heparin phosphorylates tau on Ser199, Thr231, Ser235, Ser262, Ser369, and Ser400 sites phosphorylated in Alzheimer disease brain.

1 reference

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21 January 2018

Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

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21 January 2018

Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells

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21 January 2018

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

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21 January 2018

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

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21 January 2018

Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons

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21 January 2018

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

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Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules

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GSK3: a SHAGGY frog story

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The interrelationship between selective tau phosphorylation and microtubule association

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Protein kinase FA/GSK-3 phosphorylates tau on Ser235-Pro and Ser404-Pro that are abnormally phosphorylated in Alzheimer's disease brain.

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Protein kinase FA/glycogen synthase kinase-3 alpha after heparin potentiation phosphorylates tau on sites abnormally phosphorylated in Alzheimer's disease brain

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Differential tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase F(A)/GSK-3alpha in well and poorly differentiated human prostate carcinoma cells

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Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

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Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

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Presenilin 1 interaction in the brain with a novel member of the Armadillo family

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Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5.

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7 January 2021

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10.1016/S0014-5793(99)00741-3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10413115%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10413115%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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