TBX2 overexpression promotes proliferation and invasion through epithelial-mesenchymal transition and ERK signaling pathway (Q60931566)

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article by Xingyu Liu et al published January 2019 in Experimental and Therapeutic Medicine

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English	TBX2 overexpression promotes proliferation and invasion through epithelial-mesenchymal transition and ERK signaling pathway	article by Xingyu Liu et al published January 2019 in Experimental and Therapeutic Medicine

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scholarly article

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TBX2 overexpression promotes proliferation and invasion through epithelial-mesenchymal transition and ERK signaling pathway (English)

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author name string

Xingyu Liu

1

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Zhifeng Miao

2

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Zhenning Wang

3

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Tingting Zhao

4

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Yingying Xu

5

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Yongxi Song

6

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Jinyu Huang

7

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Junyan Zhang

8

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Hao Xu

9

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Jianhua Wu

10

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Huimian Xu

11

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language of work or name

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publication date

January 2019

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number of pages

7

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Experimental and Therapeutic Medicine

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17

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723-729

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6307397/fullTextXML

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The T-box gene family

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Cyclin D3: requirement for G1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Conserved and divergent expression of T-box genes Tbx2-Tbx5 in Xenopus

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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[Functional evolution of T-box gene family on animal development]

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Matrix metalloproteinases (MMPs) in breast cancer cell lines of different tumorigenicity

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Conserved expression control and shared activity between cognate T-box genes Tbx2 and Tbx3 in connection with Sonic hedgehog signaling during Xenopus eye development.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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T-box binding protein type two (TBX2) is an immediate early gene target in retinoic-acid-treated B16 murine melanoma cells

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Tbx2 represses expression of Connexin43 in osteoblastic-like cells.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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The Drosophila melanogaster T-box genes midline and H15 are conserved regulators of heart development

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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[The expression of matrix metalloproteinases (MMPs), tissue inhibitor of metalloproteinases (TIMPs) and angiogenesis in relation to the depth of tumor invasion and lymph node metastasis in submucosally invasive colorectal carcinoma]

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Cell cycle regulation of the T-box transcription factor tbx2.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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T-box proteins differentially activate the expression of the endogenous interferon gamma gene versus transfected reporter genes in non-immune cells

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Expression and clinical significance of tbx2 in pancreatic cancer

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Expression of the oscillating gene her1 is directly regulated by Hairy/Enhancer of Split, T-box, and Suppressor of Hairless proteins in the zebrafish segmentation clock

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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The T-box transcription factor Tbx2: its role in development and possible implication in cancer

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Expression of PSCA, PIWIL1, and TBX2 in endometrial adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Differential expression patterns of MMPs and their role in the invasion of epithelial premalignant tumors and invasive cutaneous squamous cell carcinoma.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancer

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Beyond the binding site: in vivo identification of tbx2, smarca5 and wnt5b as molecular targets of CNBP during embryonic development.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Increased expression of TBX2 is a novel independent prognostic biomarker of a worse outcome in colorectal cancer patients after curative surgery and a potential therapeutic target

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Bmi-1-shRNA inhibits the proliferation of lung adenocarcinoma cells by blocking the G1/S phase through decreasing cyclin D1 and increasing p21/p27 levels

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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The T-box gene family: emerging roles in development, stem cells and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Metformin improves survival and recurrence rate in patients with diabetes and gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Association of TBX2 and P21 expression with clinicopathological features and survival of laryngeal squamous cell carcinoma

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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T-box transcription factor Brachyury in lung cancer cells inhibits macrophage infiltration by suppressing CCL2 and CCL4 chemokines

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Trends in gastric cancer incidence: a period and birth cohort analysis in a well-defined French population

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Incidence of gastric cancer after endoscopic resection of gastric adenoma.

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Impact of c-erbB-2 protein on 5-year survival rate of gastric cancer patients after surgery: a cohort study and meta-analysis

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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T-box 2 expression predicts poor prognosis in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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EphA2 is a key effector of the MEK/ERK/RSK pathway regulating glioblastoma cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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T-box transcription factor brachyury promotes tumor cell invasion and metastasis in non-small cell lung cancer via upregulation of matrix metalloproteinase 12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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DDR1 enhances invasion and metastasis of gastric cancer via epithelial-mesenchymal transition

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Overexpressed MALAT1 promotes invasion and metastasis of gastric cancer cells via increasing EGFL7 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Wogonin inhibits the proliferation and invasion, and induces the apoptosis of HepG2 and Bel7402 HCC cells through NF‑κB/Bcl-2, EGFR and EGFR downstream ERK/AKT signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Trends in gastric and esophageal cancer incidence in northern Portugal (1994-2009) by subsite and histology, and predictions for 2015.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Gastric cancer mortality in a high-incidence area (Ardabil Province, Northwest Iran): What risk factors are causative?

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Neurotrophic Factor-α1: A Key Wnt-β-Catenin Dependent Anti-Proliferation Factor and ERK-Sox9 Activated Inducer of Embryonic Neural Stem Cell Differentiation to Astrocytes in Neurodevelopment

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Tetrandrine Exerts a Radiosensitization Effect on Human Glioma through Inhibiting Proliferation by Attenuating ERK Phosphorylation

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Bone Metastasis of Prostate Cancer Can Be Therapeutically Targeted at the TBX2-WNT Signaling Axis

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https://pubmed.ncbi.nlm.nih.gov/30651856

12 December 2020

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Identifiers

10.3892/ETM.2018.7028

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