Both CD4+ FoxP3+ and CD4+ FoxP3- T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro (Q61883561)

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scientific article published in July 2011

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English	Both CD4+ FoxP3+ and CD4+ FoxP3- T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro	scientific article published in July 2011

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27 January 2020

Both CD4+ FoxP3+ and CD4+ FoxP3- T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro (English)

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27 January 2020

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Angelica Loskog

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27 January 2020

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Gunilla Enblad

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27 January 2020

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Camilla A Lindqvist

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27 January 2020

Lisa H Christiansson

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27 January 2020

Ingrid Thörn

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27 January 2020

Sara Mangsbo

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27 January 2020

Gabriella Paul-Wetterberg

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27 January 2020

Christer Sundström

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27 January 2020

Thomas H Tötterman

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27 January 2020

Bengt Simonsson

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27 January 2020

Per Frisk

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27 January 2020

Ulla Olsson-Strömberg

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27 January 2020

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5 April 2011

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27 January 2020

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27 January 2020

133

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27 January 2020

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27 January 2020

296-306

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27 January 2020

Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of CD4+CD25(high) FOXP3+ Tregs in lymphomas and tumors are complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How regulatory T cells work

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between CD107a expression and cytotoxic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The many roles of FAS receptor signaling in the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Appraisal of immune response in lymphoproliferative syndromes: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural aspects of the FOXP3 regulatory complex as an immunopharmacological target

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: Regulatory T cells directly suppress B cells in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A unifying microenvironment model in follicular lymphoma: outcome is predicted by programmed death-1--positive, regulatory, cytotoxic, and helper T cells and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patients with B cell chronic lymphocytic leukaemia have an expanded population of CD4 perforin expressing T cells enriched for human cytomegalovirus specificity and an effector-memory phenotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cytotoxic and regulatory T cells in relapsed/refractory Hodgkin lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD4+ cytotoxic T lymphocytes in the control of viral diseases and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered B cell development and anergy in the absence of Foxp3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T regulatory cells control T-cell proliferation partly by the release of soluble CD25 in patients with B-cell malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigens in chronic lymphocytic leukemia--implications for cell origin and leukemogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential role for Scurfin in CD4+CD25+ T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ T Cells Lyse Antigen-Presenting B Cells by Fas-Fas Ligand Interaction in an Epitope-Specific Manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic CD4+ T cells in patients with B cell chronic lymphocytic leukemia kill via a perforin-mediated pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that chronic lymphocytic leukemia B lymphocytes are frequently committed to production of natural autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular factors that regulate the differentiation and apoptosis of germinal center B cells. Anti-Ig down-regulates Fas expression of CD40 ligand-stimulated germinal center B cells and inhibits Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of selection and differentiation in germinal centers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcome in Hodgkin's lymphoma can be predicted from the presence of accompanying cytotoxic and regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of B-cell lymphoma pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune and Chronic Inflammatory Disorders and Risk of Non-Hodgkin Lymphoma by Subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated CD4+CD25+ T cells selectively kill B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ratio of FOXP3+ regulatory T cells to granzyme B+ cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic impact of tumor infiltrating FOXP3 positive regulatory T cells in diffuse large B-cell lymphoma at diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of high numbers of intratumoral FOXP3+ regulatory T cells with improved survival in germinal center-like diffuse large B-cell lymphoma, follicular lymphoma and classical Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forced overexpression of either of the two common human Foxp3 isoforms can induce regulatory T cells from CD4(+)CD25(-) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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