Wild-type CYP102A1 as a biocatalyst: turnover of drugs usually metabolised by human liver enzymes (Q61978849)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Wild-type CYP102A1 as a biocatalyst: turnover of drugs usually metabolised by human liver enzymes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Giovanna Di Nardo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Andrea Fantuzzi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Anastasia Sideri

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Paola Panicco

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Carlo Sassone

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Carlo Giunta

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

publication date

18 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Inorganic Chemistry

24 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

313-323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

Laboratory evolution of cytochrome p450 BM-3 monooxygenase for organic cosolvents

24 December 2019

cites work

1 reference

12 December 2020

Simplified high-performance liquid chromatographic method for propranolol and five metabolites in liver perfusate, rat serum and dog plasma

1 reference

12 December 2020

Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450.

1 reference

12 December 2020

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

1 reference

12 December 2020

Probing electron transfer in flavocytochrome P-450 BM3 and its component domains.

1 reference

12 December 2020

Molecular evolution of P450 superfamily and P450-containing monooxygenase systems

1 reference

12 December 2020

Contribution of human CYP3A subfamily members to the 6-hydroxylation of chlorzoxazone

1 reference

12 December 2020

Evaluation of alkoxyresorufins as fluorescent substrates for cytochrome P450 BM3 and site-directed mutants.

1 reference

12 December 2020

Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.

1 reference

12 December 2020

Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes

1 reference

12 December 2020

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

1 reference

12 December 2020

Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression

1 reference

12 December 2020

Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego.

1 reference

12 December 2020

High throughput assay for cytochrome P450 BM3 for screening libraries of substrates and combinatorial mutants

1 reference

12 December 2020

Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome P450s

1 reference

12 December 2020

Cytochromes P450, drugs, and diseases

1 reference

12 December 2020

Species difference in enantioselectivity for the oxidation of propranolol by cytochrome P450 2D enzymes

1 reference

12 December 2020

Metabolite profiling study of propranolol in rat using LC/MS/MS analysis

1 reference

12 December 2020

Rational re-design of the substrate binding site of flavocytochrome P450 BM3

1 reference

12 December 2020

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

1 reference

12 December 2020

Uncommon P450-catalyzed reactions

1 reference

12 December 2020

Oxidizing species in the mechanism of cytochrome P450.

1 reference

12 December 2020

CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development

1 reference

12 December 2020

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

1 reference

12 December 2020

Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.

1 reference

12 December 2020

Both cytochromes P450 2E1 and 3A are involved in the O-hydroxylation of p-nitrophenol, a catalytic activity known to be specific for P450 2E1

1 reference

12 December 2020

Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics

1 reference

12 December 2020

Assay of formaldehyde generated during microsomal oxidation reactions

1 reference

12 December 2020

Roles of key active-site residues in flavocytochrome P450 BM3

1 reference

12 December 2020

Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.

1 reference

12 December 2020

Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis.

1 reference

12 December 2020

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism

1 reference

12 December 2020

P450 BM3: the very model of a modern flavocytochrome

1 reference

12 December 2020

Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s

1 reference

12 December 2020

Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3.

1 reference

12 December 2020

Rapid and quantitative determination of metabolites from multiple cytochrome P450 probe substrates by gradient liquid chromatography-electrospray ionization-ion trap mass spectrometry

1 reference

12 December 2020

Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium.

1 reference

12 December 2020

Simultaneous determination of nifedipine and dehydronifedipine in human plasma by liquid chromatography-tandem mass spectrometry.

1 reference

12 December 2020

Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium

1 reference

12 December 2020

High-performance liquid chromatographic assay for 4-nitrophenol hydroxylation, a putative cytochrome P-4502E1 activity, in human liver microsomes

1 reference

12 December 2020

10.1007/S00775-006-0188-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235582%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference