Aminocyclitol-Substituted Phytoceramides and their Effects on iNKT Cell Stimulation (Q61986624)

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7 February 2020

title

Aminocyclitol-substituted phytoceramides and their effects on iNKT cell stimulation (English)

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7 February 2020

0 references

2

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7 February 2020

Carmen Bedia

3

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7 February 2020

A R Castaño

5

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7 February 2020

Amadeu Llebaria

6

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7 February 2020

author name string

Youssef Harrak

1

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7 February 2020

Antonio Delgado

4

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publication date

1 October 2009

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7 February 2020

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7 February 2020

volume

4

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issue

10

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page(s)

1608-1613

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7 February 2020

cites work

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Immune regulation by invariant NKT cells in autoimmunity

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CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

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Glycolipid antigen induces long-term natural killer T cell anergy in mice

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Glycolipids as immunostimulating agents

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A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR.

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The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation

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Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides

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RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines

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7 January 2021

RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines

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Synthesis of alpha-galactosyl ceramide (KRN7000) and analogues thereof via a common precursor and their preliminary biological assessment.

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7 January 2021

Structure-activity relationship of alpha-galactosylceramides against B16-bearing mice

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7 January 2021

Synthesis and biological evaluation of alpha-galactosylceramide (KRN7000) and isoglobotrihexosylceramide (iGb3).

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7 January 2021

Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Vα14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids

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7 January 2021

Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides

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7 January 2021

6'-derivatised alpha-GalCer analogues capable of inducing strong CD1d-mediated Th1-biased NKT cell responses in mice.

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7 January 2021

Synthesis and NKT cell stimulating properties of fluorophore- and biotin-appended 6"-amino-6"-deoxy-galactosylceramides.

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7 January 2021

The C-Glycoside Analogue of the Immunostimulantα-Galactosylceramide (KRN7000): Synthesis and Striking Enhancement of Activity

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7 January 2021

The first synthesis of a thioglycoside analogue of the immunostimulant KRN7000

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7 January 2021

Alpha-S-GalCer: synthesis and evaluation for iNKT cell stimulation

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7 January 2021

Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-Galactosylceramide

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7 January 2021

Nonglycosidic agonists of invariant NKT cells for use as vaccine adjuvants

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7 January 2021

Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells

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7 January 2021

Aminocyclitols as pharmacological chaperones for glucocerebrosidase, a defective enzyme in Gaucher disease

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7 January 2021

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7 January 2021

Combinatorial approach to N-substituted aminocyclitol libraries by solution-phase parallel synthesis and preliminary evaluation as glucocerebrosidase inhibitors

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7 January 2021

Regio- and stereoselective synthesis of aminoinositols and 1,2-diaminoinositols from conduritol B epoxide

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7 January 2021

On the regio- and stereoselective synthesis of aminocyclitols from cyclitol epoxides: the effect of Li as a chelating agent.

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7 January 2021

Practical synthesis of (-)-1-amino-1-deoxy-myo-inositol from achiral precursors

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7 January 2021

CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution

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7 January 2021

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

A pegylated derivative of alpha-galactosylceramide exhibits improved biological properties

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7 January 2021

Identifiers

DOI

10.1002/CMDC.200900193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19739197%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference