CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans (Q62494307)

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12 February 2020

title

CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans (English)

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12 February 2020

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4

Collen Masimirembwa

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author name string

Milimo Maimbo

1

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12 February 2020

Kazuma Kiyotani

2

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12 February 2020

Taisei Mushiroda

3

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12 February 2020

Yusuke Nakamura

5

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12 February 2020

Collen Masimirembwa

4

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12 February 2020

language of work or name

English

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publication date

8 September 2011

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European Journal of Clinical Pharmacology

12 February 2020

published in

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12 February 2020

volume

68

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12 February 2020

issue

3

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page(s)

267-271

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Liver toxicity induced by non-nucleoside reverse transcriptase inhibitors.

12 February 2020

cites work

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12 December 2020

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe

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12 December 2020

Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients

1 reference

12 December 2020

Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations

1 reference

12 December 2020

High prevalence of cytochrome P450 2A6*1A alleles in a black African population of Ghana

1 reference

12 December 2020

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

1 reference

12 December 2020

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

1 reference

12 December 2020

Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz

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12 December 2020

Safety and efficacy of nevirapine- and efavirenz-based antiretroviral treatment in adults treated for TB-HIV co-infection in Botswana

1 reference

12 December 2020

Outcomes of nevirapine- and efavirenz-based antiretroviral therapy when coadministered with rifampicin-based antitubercular therapy

1 reference

12 December 2020

Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

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12 December 2020

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

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12 December 2020

Twenty one novel single nucleotide polymorphisms (SNPs) of the CYP2A6 gene in Japanese and Caucasians

1 reference

12 December 2020

Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylation

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12 December 2020

Effects of CYP2B6 G516T polymorphisms on plasma efavirenz and nevirapine levels when co-administered with rifampicin in HIV/TB co-infected Thai adults

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12 December 2020

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

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12 December 2020