Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells (Q62733725)

12 December 2020

CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells.

1 reference

12 December 2020

Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation

1 reference

12 December 2020

B7/CD28 but not LFA-3/CD2 interactions can provide 'third-party' co-stimulation for human T-cell activation

1 reference

12 December 2020

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

1 reference

12 December 2020

Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase

1 reference

12 December 2020

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

1 reference

12 December 2020

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

1 reference

12 December 2020

CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity

1 reference

12 December 2020

Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells.

1 reference

12 December 2020

Role for ceramide in cell cycle arrest.

1 reference

12 December 2020

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

1 reference

12 December 2020

Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest

1 reference

12 December 2020

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

1 reference

12 December 2020

CD28 signals through acidic sphingomyelinase

1 reference

12 December 2020

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

12 December 2020

Sphingomyelin-ceramide turnover in CD28 costimulatory signaling

1 reference

12 December 2020

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

1 reference

12 December 2020

CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation

1 reference

12 December 2020

Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

1 reference

12 December 2020

1 reference

12 December 2020

CD28 costimulation inhibits TCR-induced apoptosis during a primary T cell response

1 reference

12 December 2020

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

12 December 2020

The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

1 reference

12 December 2020

CD28 costimulation prevents cell death during primary T cell activation

1 reference

12 December 2020

Phosphatidylinositol 3 kinase activity is not essential for B7-1-mediated costimulation of proliferation or development of cytotoxicity in murine T cells

1 reference

12 December 2020

The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

1 reference

12 December 2020

Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95

1 reference

12 December 2020

Stimulation of CD95 (Fas) blocks T lymphocyte calcium channels through sphingomyelinase and sphingolipids.

1 reference

12 December 2020

Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens

1 reference

12 December 2020

Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

1 reference

12 December 2020

A cell culture model for T lymphocyte clonal anergy

1 reference

12 December 2020

A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis

1 reference

12 December 2020

Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation

1 reference

12 December 2020

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

1 reference

12 December 2020

B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

1 reference

12 December 2020

TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

1 reference

12 December 2020