STAT5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver (Q62819486)

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3 November 2019

title

STAT5b mediates the GH-induced expression of SOCS-2 and SOCS-3 mRNA in the liver (English)

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3 November 2019

4

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3 November 2019

Timothy E Adams

5

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3 November 2019

author name string

H W Davey

1

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3 November 2019

M J McLachlan

2

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3 November 2019

R J Wilkins

3

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3 November 2019

publication date

1 December 1999

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Molecular and Cellular Endocrinology

3 November 2019

published in

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3 November 2019

volume

158

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3 November 2019

issue

1-2

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3 November 2019

page(s)

111-116

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

3 November 2019

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Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.

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STATs and gene regulation

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Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation

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Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

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Nucleotide sequence of the human gamma cytoskeletal actin mRNA: anomalous evolution of vertebrate non-muscle actin genes

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Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation

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A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

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Twenty proteins containing a C-terminal SOCS box form five structural classes

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Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity

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Identification of a membrane-associated inhibitor(s) of epidermal growth factor-induced signal transducer and activator of transcription activation.

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Jaks and STATs: biological implications

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Inhibition of Stat1-mediated gene activation by PIAS1

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Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

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7 January 2021

Stat5a is mandatory for adult mammary gland development and lactogenesis.

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Cloning and characterization of novel CIS family genes

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Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

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Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

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Structure and function of a new STAT-induced STAT inhibitor

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7 January 2021

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

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7 January 2021

SOCS-1/JAB/SSI-1 can bind to and suppress Tec protein-tyrosine kinase

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7 January 2021

Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.

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7 January 2021

Growth hormone activation of Stat 1, Stat 3, and Stat 5 in rat liver. Differential kinetics of hormone desensitization and growth hormone stimulation of both tyrosine phosphorylation and serine/threonine phosphorylation

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7 January 2021

SOCS: suppressors of cytokine signalling

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

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7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

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7 January 2021

Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein

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7 January 2021

A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B.

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7 January 2021

Naturally occurring dominant negative variants of Stat5.

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7 January 2021

Intermittent plasma growth hormone triggers tyrosine phosphorylation and nuclear translocation of a liver-expressed, Stat 5-related DNA binding protein. Proposed role as an intracellular regulator of male-specific liver gene transcription

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7 January 2021

Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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7 January 2021

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

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Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription

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7 January 2021

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10630411%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference