(2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione (Q63393012)

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chemical compound
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English
(2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
chemical compound

    Statements

    mass
    460.14818034799987 dalton
    1 reference
    based on heuristic
    inferred from isomeric SMILES
    chemical formula
    C₂₂H₂₄N₂O₉
    0 references
    canonical SMILES
    O=C1C(=C(O)N)C(=O)C2(O)C(=O)C3=C(O)C=4C(O)=CC=CC4C(O)(C)C3C(O)C2C1N(C)C
    0 references
    isomeric SMILES
    C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)/C(=C(\N)/O)/C(=O)[C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O)O
    0 references
    found in taxon
    Kitasatospora aureofaciens
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces aureofaciens
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces bingchenggensis
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces albidoflavus
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces coelicolor
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces diastaticus
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces lividans
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces rimosus
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces varsoviensis
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces venezuelae
    13 references
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    Streptomyces milbemycinicus
    13 references
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    Streptomyces anthocyanicus
    13 references
    stated in
    Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
    stated in
    Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length
    stated in
    Efficient bioconversion of quercetin into a novel glycoside by Streptomyces rimosus subsp. rimosus ATCC 10970
    stated in
    Production of extracellular heterologous proteins in Streptomyces rimosus, producer of the antibiotic oxytetracycline.
    stated in
    Genome Sequences of the Oxytetracycline Production Strain Streptomyces rimosus R6-500 and Two Mutants with Chromosomal Rearrangements
    stated in
    Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry
    stated in
    Morphogenesis, ATP content and oxytetracycline production by Streptomyces rimosus in solid substrate cultivation
    stated in
    Growth Inhibition of Streptomyces Species by l-Serine and Its Effect on Tetracycline Biosynthesis
    stated in
    Sequences of the oxytetracycline polyketide synthase-encoding otc genes from Streptomyces rimosus
    stated in
    Conserved organization of genes for biosynthesis of chlortetracycline in Streptomyces strains
    stated in
    The fermentative production of oxytetracycline on industrial by-products byStreptomyces rimosus 12907
    stated in
    Improvement of oxytetracycline production mediated via cooperation of resistance genes in Streptomyces rimosus.
    stated in
    Molecular cloning of tetracycline resistance genes from Streptomyces rimosus in Streptomyces griseus and characterization of the cloned genes.

    Identifiers

     
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