CpG-oligodeoxynucleotides enhance T-cell receptor-triggered interferon-gamma production and up-regulation of CD69 via induction of antigen-presenting cell-derived interferon type I and interleukin-12 (Q63407133)

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article by K Kranzer et al published February 2000 in Immunology

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English	CpG-oligodeoxynucleotides enhance T-cell receptor-triggered interferon-gamma production and up-regulation of CD69 via induction of antigen-presenting cell-derived interferon type I and interleukin-12	article by K Kranzer et al published February 2000 in Immunology

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scholarly article

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CpG-oligodeoxynucleotides enhance T-cell receptor-triggered interferon-gamma production and up-regulation of CD69 via induction of antigen-presenting cell-derived interferon type I and interleukin-12 (English)

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object named as

R Lang

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author name string

K Kranzer

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M Bauer

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G B Lipford

3

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K Heeg

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H Wagner

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language of work or name

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publication date

February 2000

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99

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2

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170-8

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Macrophages ingest and are activated by bacterial DNA.

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DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen

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CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen

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Bacterial DNA as immune cell activator

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Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma

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Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

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CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells

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CpG motifs in bacterial DNA trigger direct B-cell activation

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Rapid induction of mitogen-activated protein kinases by immune stimulatory CpG DNA.

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Synthetic Oligonucleotides with Certain Palindromes Stimulate Interferon Production of Human Peripheral Blood Lymphocytes in vitro

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Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA

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Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

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CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

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DNA activates human immune cells through a CpG sequence-dependent manner

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Semiquantitative determination of human cytokine mRna expression using TaqMan RT-PCR.

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Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants.

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The role of Stat4 in species-specific regulation of Th cell development by type I IFNs.

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CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

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Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells

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Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-gamma production in cells from allergic individuals and inhibit IgE synthesis in vitro

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Type I interferon-mediated stimulation of T cells by CpG DNA

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https://pubmed.ncbi.nlm.nih.gov/10692033

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CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10692033

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CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants

1 reference

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CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10692033

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Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines

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Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells

1 reference

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Identifiers

10.1046/J.1365-2567.2000.00964.X

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