Multiple Regulatory Elements in the 5′-Flanking Sequence of the Human ε-Globin Gene (Q63433340)

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11 November 2019

title

Multiple regulatory elements in the 5'-flanking sequence of the human epsilon-globin gene (English)

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11 November 2019

4

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11 November 2019

Alan Neil Schechter

5

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11 November 2019

author name string

J Li

1

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11 November 2019

C T Noguchi

2

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11 November 2019

W Miller

3

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11 November 2019

language of work or name

English

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publication date

1 April 1998

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Journal of Biological Chemistry

11 November 2019

published in

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11 November 2019

volume

273

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11 November 2019

issue

17

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11 November 2019

page(s)

10202-10209

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Chromatin structure and gene expression

11 November 2019

cites work

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Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene

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Positive and negative regulatory elements of the rabbit embryonic epsilon-globin gene revealed by an improved multiple alignment program and functional analysis.

21 January 2018

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The complete sequences of the galago and rabbit beta-globin locus control regions: extended sequence and functional conservation outside the cores of DNase hypersensitive sites.

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Human gamma- to beta-globin gene switching in transgenic mice.

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The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice

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Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice.

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Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene

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Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice

21 January 2018

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Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

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Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis.

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Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements

21 January 2018

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Sequence and linkage of the goat epsilon I and epsilon II beta-globin genes

21 January 2018

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CACC box and enhancer response of the human embryonic epsilon globin promoter

21 January 2018

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Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2

21 January 2018

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A novel developmental regulatory motif required for stage-specific activation of the epsilon-globin gene and nuclear factor binding in embryonic erythroid cells

21 January 2018

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Upstream regulatory region of the human embryonic beta-like globin gene, epsilon.

21 January 2018

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Binary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expression

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The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element.

21 January 2018

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FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.17.10202

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11 November 2019

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