Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses (Q64378490)

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English	Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses	article

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4 January 2020

Characterization of hemodynamic events following intravascular infusion of recombinant adenovirus reveals possible solutions for mitigating cardiovascular responses (English)

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4 January 2020

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Todd Machemer

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4 January 2020

Heidrun Engler

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4 January 2020

Van Tsai

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4 January 2020

Seoju Lee

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4 January 2020

Susan Cannon-Carlson

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Marcio Voloch

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Thomas Schluep

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4 January 2020

Sundari Ravindran

8

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4 January 2020

Gary Vellekamp

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Elena Brin

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Douglas Cornell

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Suganto Sutjipto

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Shu Fen Wen

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4 January 2020

Mark Horn

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4 January 2020

Nico Van Rooijen

15

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4 January 2020

Dan Maneval

16

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4 January 2020

Beth Hutchins

17

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4 January 2020

Drake LaFace

18

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1 August 2005

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4 January 2020

Molecular Therapy

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4 January 2020

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4 January 2020

2

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254-263

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4 January 2020

Systemic interleukin-6 responses following administration of adenovirus gene transfer vectors to humans by different routes

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Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits

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Toxicity of a first-generation adenoviral vector in rhesus macaques

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Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

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Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

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A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency

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Intravascular adenoviral agents in cancer patients: lessons from clinical trials

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Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

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Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

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Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery

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Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity

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The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors

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The release of inflammatory cytokines from human peripheral blood mononuclear cells in vitro following exposure to adenovirus variants and capsid

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

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Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells

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A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells

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Specific depletion of human anti-adenovirus antibodies facilitates transduction in an in vivo model for systemic gene therapy.

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Functional evidence for the rapid desensitization of 5-HT(3) receptors on vagal afferents mediating the Bezold-Jarisch reflex

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Beta-adrenoceptor dysfunction after inhibition of NO synthesis

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Heterologous desensitization of beta-adrenoceptor signal transduction in vivo

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Focal modification of electrical conduction in the heart by viral gene transfer

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Porcine toxicology studies of SCH 58500, an adenoviral vector for the p53 gene

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Purification of a type 5 recombinant adenovirus encoding human p53 by column chromatography

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Analytical anion-exchange HPLC of recombinant type-5 adenoviral particles

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Multiplicity of infection/multiplicity of confusion

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Empty capsids in column-purified recombinant adenovirus preparations

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Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

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Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

1 reference

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7 January 2021

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10.1016/J.YMTHE.2005.03.007

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4 January 2020

1 reference

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4 January 2020

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