3' cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP (Q64379456)

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6 October 2019

title

3' cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP (English)

1 reference

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6 October 2019

author name string

G Christofori

series ordinal

1

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6 October 2019

W Keller

series ordinal

2

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6 October 2019

language of work or name

English

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publication date

1 September 1988

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6 October 2019

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6 October 2019

volume

54

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6 October 2019

issue

6

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6 October 2019

page(s)

875-889

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U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation

6 October 2019

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The 3' splice site of pre-messenger RNA is recognized by a small nuclear ribonucleoprotein

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The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs

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Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

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A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

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Mutations in poly(A) site downstream elements affect in vitro cleavage activity

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Poly(A) site cleavage in a HeLa nuclear extract is dependent on downstream sequences.

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A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro

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Splicing of in vitro synthesized messenger RNA precursors in HeLa cell extracts

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Alpha-thalassaemia caused by a polyadenylation signal mutation.

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Cleavage and polyadenylation of messenger RNA precursors in vitro occurs within large and specific 3' processing complexes.

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Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro.

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7 January 2021

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

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Complex transcriptional units: diversity in gene expression by alternative RNA processing

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RNA-protein organization of U1, U5 and U4-U6 small nuclear ribonucleoproteins in HeLa cells.

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RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro

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7 January 2021

Requirement of a downstream sequence for generation of a poly(A) addition site

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Multiple factors are required for poly(A) addition to a mRNA 3' end

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7 January 2021

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini

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Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

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Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

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A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly

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7 January 2021

Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro

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7 January 2021

Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.

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7 January 2021

Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs

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7 January 2021

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Structural and functional characterization of mouse U7 small nuclear RNA active in 3' processing of histone pre-mRNA

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In vitro cleavage of the simian virus 40 early polyadenylation site adjacent to a required downstream TG sequence

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7 January 2021

Assembly of a polyadenylation-specific 25S ribonucleoprotein complex in vitro

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Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

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A protein that specifically recognizes the 3' splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

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7 January 2021

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

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7 January 2021

A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif

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7 January 2021

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro

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7 January 2021

Identification of a complex associated with processing and polyadenylation in vitro of herpes simplex virus type 1 thymidine kinase precursor RNA

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7 January 2021

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6 October 2019

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