Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes (Q64388057)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

L H Meng

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

J S Zhang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

J Ding

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

language of work or name

English

0 references

publication date

1 September 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

733-741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

Synthesis and antitumour activity of novel diterpenequinone salvicine and the analogs

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Induction of apoptosis in human leukemia K-562 and gastric carcinoma SGC-7901 cells by salvicine, a novel anticancer compound

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Covalent attachment of ethidium to DNA results in enhanced topoisomerase II-mediated DNA cleavage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

The ortho-quinone metabolite of the anticancer drug etoposide (VP-16) is a potent inhibitor of the topoisomerase II/DNA cleavable complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Effect of antineoplastic agents on the DNA cleavage/religation reaction of eukaryotic topoisomerase II: inhibition of DNA religation by etoposide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

DNA unwinding and inhibition of T4 DNA ligase by anthracyclines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Investigating the biological functions of DNA topoisomerases in eukaryotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Clinical applications of anticancer drugs targeted to topoisomerase II

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Phase I and pharmacokinetic study of DACA (XR5000): a novel inhibitor of topoisomerase I and II. CRC Phase I/II Committee

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Topoisomerase I/II inhibitor intoplicine administered as a 24 h infusion: phase I and pharmacologic study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

S16020-2, a new highly cytotoxic antitumor olivacine derivative: DNA interaction and DNA topoisomerase II inhibition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

DNA sequence selectivity of topoisomerases and topoisomerase poisons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Topoisomerase II.etoposide interactions direct the formation of drug-induced enzyme-DNA cleavage complexes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

Cellular resistance to topoisomerase-targeted drugs: from drug uptake to cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

A mutation in yeast topoisomerase II that confers hypersensitivity to multiple classes of topoisomerase II poisons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2801%2900732-8

10.1016/S0006-2952(01)00732-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551518%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference