lenvatinib (Q6523413)

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chemical compound

E 7080
ER-203492-00
Lenvima®
UNII-EE083865G2
E7080
4-(3-Chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
Lenvatinib
4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide
Lenvatinib Mesylate
Lenvima

Language	Label	Description	Also known as
English	lenvatinib	chemical compound	E 7080 ER-203492-00 Lenvima® UNII-EE083865G2 E7080 4-(3-Chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide Lenvatinib 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide Lenvatinib Mesylate Lenvima

Statements

type of chemical entity

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chemical compound

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chemical structure

Lenvatinib skeletal.svg
512 × 279; 6 KB

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426.109 dalton

1 reference

language of work or name

Lenvatinib (English)

19 October 2016

chemical formula

C₂₁H₁₉ClN₄O₄

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

canonical SMILES

COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

active ingredient in

1 reference

14 February 2018

World Health Organisation international non-proprietary name

lenvatinib (English)

1 reference

language of work or name

lenvatinib (English)

19 October 2016

medical condition treated

renal clear cell carcinoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

renal cell carcinoma

1 reference

Drug Indications Extracted from FAERS

2 October 2018

Tuberculosis (possibly)

1 reference

Drug Indications Extracted from FAERS

2 October 2018

thyroid cancer, nonmedullary, 1

1 reference

Drug Indications Extracted from FAERS

2 October 2018

1 reference

Drug Indications Extracted from FAERS

2 October 2018

anaplastic thyroid cancer

1 reference

Drug Indications Extracted from FAERS

2 October 2018

physically interacts with

Fms related receptor tyrosine kinase 4

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Kinase insert domain receptor

subject has role

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

LiverTox likelihood score

LiverTox toxicity likelihood category D

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Lenvatinib

1 June 2017

subject has role

protein kinase inhibitors

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Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

Commons category

Lenvatinib

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Identifiers

InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

WOSKHXYHFSIKNG-UHFFFAOYSA-N

2 references

language of work or name

Lenvatinib (English)

20 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

lenvatinib (English)

20 November 2016

CAS Common Chemistry

7 April 2021

https://commonchemistry.cas.org/detail?cas_rn=417716-92-8

WOSKHXYHFSIKNG-UHFFFAOYSA-N

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

Reaxys registry number

12096874

1 reference

language of work or name

lenvatinib (English)

19 October 2016

mapping relation type

2 references

language of work or name

LENVATINIB (English)

20 November 2016

matched by identifier from

International Chemical Identifier

InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)

1 reference

language of work or name

LENVATINIB (English)

20 November 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

WOSKHXYHFSIKNG-UHFFFAOYSA-N

UniChem compound ID

1 reference

DSSTox substance ID

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

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Guide to Pharmacology Ligand ID

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

lenvatinib (English)

20 November 2016

MeSH descriptor ID

subject named as

lenvatinib

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

Global Substance Registration System

language of work or name

lenvatinib (English)

20 November 2016

1 reference

language of work or name

Lenvatinib (English)

20 November 2016

Human Metabolome Database ID

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

WOSKHXYHFSIKNG-UHFFFAOYSA-N

2 references

Global Substance Registration System

language of work or name

lenvatinib (English)

20 November 2016

matched by identifier from

WOSKHXYHFSIKNG-UHFFFAOYSA-N

MedlinePlus drug identifier

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PatientsLikeMe treatment ID

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1 reference

Global Substance Registration System

language of work or name

lenvatinib (English)

20 November 2016

Probes And Drugs ID

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1 reference

1 reference

language of work or name

lenvatinib (English)

19 October 2016

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Microsoft Academic ID

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1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

Protein Data Bank

PDB structure ID

language of work or name

3WZD (English)

19 October 2016

1 reference

Global Substance Registration System

language of work or name

lenvatinib (English)

20 November 2016

WikiProjectMed ID

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Sitelinks

Wikipedia(11 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Lenvatinib

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