Glutamate metabotropic receptor 6 (Q6589868)

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mammalian protein found in Homo sapiens

• metabotropic glutamate receptor 6
• GRM6
• glutamate receptor, metabotropic 6

edit

Language	Label	Description	Also known as
English	Glutamate metabotropic receptor 6	mammalian protein found in Homo sapiens	metabotropic glutamate receptor 6 GRM6 glutamate receptor, metabotropic 6

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O15303

part of

GPCR, family 3, metabotropic glutamate receptor 6

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

Periplasmic binding protein-like I

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

GPCR, family 3, nine cysteines domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

Receptor, ligand binding region, protein family

1 reference

based on heuristic

inferred from protein domain or family

GPCR family 3, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GPCR, family 3, nine cysteines domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GPCR, family 3, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O15303

encoded by

GRM6

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O15303

molecular function

glutamate receptor activity

determination method

TAS

IMP

2 references

retrieved

5 June 2018

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

5 June 2018

stated in

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

IMP

G protein-coupled receptor activity

determination method

TAS

IEA

3 references

retrieved

8 April 2019

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

protein homodimerization activity

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IPI

signal transducer activity

determination method

IEA

1 reference

retrieved

31 October 2017

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

IEA

adenylate cyclase inhibiting G protein-coupled glutamate receptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IPI

glutamate receptor activity

determination method

IBA

IMP

TAS

3 references

retrieved

8 April 2019

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IMP

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

cell component

integral component of membrane

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

Golgi apparatus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

cell projection

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

endoplasmic reticulum membrane

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IDA

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

Golgi membrane

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IDA

plasma membrane

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

integral component of plasma membrane

determination method

IDA

TAS

2 references

retrieved

5 June 2018

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

5 June 2018

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

IDA

dendrite

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

endoplasmic reticulum

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

presynaptic membrane

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

new growing cell tip

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

integral component of plasma membrane

determination method

IBA

IDA

TAS

3 references

retrieved

8 April 2019

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

biological process

G protein-coupled glutamate receptor signaling pathway

determination method

TAS

IMP

2 references

retrieved

5 June 2018

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

5 June 2018

stated in

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15303&geneProductId=UniProtKB:O15303

determination method

IMP

detection of visible light

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

locomotory behavior

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

response to stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

sensory perception of light stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

detection of light stimulus involved in visual perception

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IMP

positive regulation of calcium ion import

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IMP

retina development in camera-type eye

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

signal transduction

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

visual perception

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

chemical synaptic transmission

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

regulation of synaptic transmission, glutamatergic

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

G protein-coupled receptor signaling pathway

determination method

IEA

TAS

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IEA

adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

determination method

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

G protein-coupled glutamate receptor signaling pathway

determination method

IBA

IMP

TAS

3 references

retrieved

8 April 2019

stated in

The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

TAS

retrieved

8 April 2019

stated in

Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes

GOA

curator

UniProt

UniProt protein ID

O15303

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IMP

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15303

determination method

IBA

physically interacts with

eglumetad

has use

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1393

language of work or name

English

retrieved

17 August 2016

DCPG

has use

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1407

language of work or name

English

retrieved

17 August 2016

L-AP4

has use

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1410

language of work or name

English

retrieved

17 August 2016

LY379268

has use

agonist

1 reference

stated in

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1394

language of work or name

English

retrieved

17 August 2016

Gene Atlas image

PBB GE GRM6 208035 at fs.png
732 × 530; 12 KB

0 references

has part(s)

GPCR, family 3, nine cysteines domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

Receptor, ligand binding region

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

GPCR, family 3, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

GPCR family 3, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O15303

Identifiers

RefSeq protein ID

NP_000834

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

2916

UniProt protein ID

O15303

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O15303

Ensembl protein ID

ENSP00000231188

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000231188

ENSP00000430767

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430767

ENSP00000497110

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000497110

Freebase ID

/m/03d4qh9

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

56940625

0 references

OpenAlex ID

C56940625

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

 

Sitelinks

Wikipedia(6 entries)

edit

• dewiki Metabotroper Glutamatrezeptor 6
• enwiki Metabotropic glutamate receptor 6
• ptwiki Receptor metabotrópico de glutamato 6
• shwiki Metabotropni glutamatni receptor 6
• srwiki Metabotropni glutamatni receptor 6
• ukwiki GRM6

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q6589868&oldid=2022908852"