MHC class I polypeptide-related sequence A (Q6715825)

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mammalian protein found in Homo sapiens

MHC class I related chain A
HLA class I antigen
truncated MICA
MHC class I chain-related protein A
MHC class I related sequence A
stress inducible class I homolog
major histocompatibility complex class I chain-related protein A
MICA
truncated MHC class I polypeptide-related sequence A

Language	Label	Description	Also known as
English	MHC class I polypeptide-related sequence A	mammalian protein found in Homo sapiens	MHC class I related chain A HLA class I antigen truncated MICA MHC class I chain-related protein A MHC class I related sequence A stress inducible class I homolog major histocompatibility complex class I chain-related protein A MICA truncated MHC class I polypeptide-related sequence A

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

MHC classes I/II-like antigen recognition protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

MHC class I-like antigen recognition-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

MHC class I-like antigen recognition-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin C1-set, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

beta-2-microglobulin binding

determination method

1 reference

8 April 2019

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

natural killer cell lectin-like receptor binding

determination method

natural killer cell lectin-like receptor binding

determination method

3 references

8 April 2019

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

8 April 2019

Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Tumor-associated MICA is shed by ADAM proteases

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

extracellular space

determination method

1 reference

10 September 2018

Tumor-associated MICA is shed by ADAM proteases

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q29983&geneProductId=UniProtKB:Q29983

determination method

plasma membrane

determination method

external side of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

biological process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

adaptive immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

negative regulation of natural killer cell activation

determination method

1 reference

8 April 2019

Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

gamma-delta T cell activation

determination method

1 reference

8 April 2019

Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

response to heat

determination method

1 reference

8 April 2019

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

immune response to tumor cell

determination method

1 reference

8 April 2019

Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

cellular response to DNA damage stimulus

determination method

1 reference

8 April 2019

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

defense response to bacterium

determination method

regulation of immune response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

negative regulation of natural killer cell mediated cytotoxicity

determination method

1 reference

8 April 2019

Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

T cell mediated cytotoxicity

determination method

1 reference

27 March 2018

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q29983&geneProductId=UniProtKB:Q29983

determination method

natural killer cell mediated cytotoxicity

determination method

1 reference

27 March 2018

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q29983&geneProductId=UniProtKB:Q29983

determination method

immune response

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

natural killer cell activation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

susceptibility to natural killer cell mediated cytotoxicity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q29983

determination method

Gene Atlas image

PBB GE MICA 205904 at fs.png
732 × 530; 11 KB

0 references

immunoglobulin C1-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

MHC class I-like antigen recognition-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q29983

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000383179

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383179

ENSP00000402134

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402134

ENSP00000446963

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000446963

ENSP00000407264

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000407264

ENSP00000491615

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000491615

ENSP00000433021

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433021

ENSP00000413079

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413079

ENSP00000394553

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000394553

ENSP00000446655

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000446655

ENSP00000482763

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482763

ENSP00000482382

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482382

ENSP00000383176

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383176

ENSP00000492562

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492562

ENSP00000412989

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412989

ENSP00000398552

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398552

ENSP00000404397

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000404397

ENSP00000412992

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412992

ENSP00000409422

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000409422

ENSP00000447026

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000447026

ENSP00000402410

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402410

ENSP00000405741

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405741

ENSP00000395954

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395954

ENSP00000405177

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000405177

ENSP00000416941

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000416941

ENSP00000480992

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000480992

ENSP00000395645

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395645

ENSP00000500967

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000500967

ENSP00000501157

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000501157

ENSP00000501002

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000501002

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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