A new cardiotonic agent, OPC-8212, elevates the myocardial oxygen consumption versus pressure-volume area (PVA) relation in a similar manner to catecholamines and calcium in canine hearts (Q68073754)

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scientific article published on 01 January 1988

Language	Label	Description	Also known as
English	A new cardiotonic agent, OPC-8212, elevates the myocardial oxygen consumption versus pressure-volume area (PVA) relation in a similar manner to catecholamines and calcium in canine hearts	scientific article published on 01 January 1988

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

A new cardiotonic agent, OPC-8212, elevates the myocardial oxygen consumption versus pressure-volume area (PVA) relation in a similar manner to catecholamines and calcium in canine hearts (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

author name string

S Futaki

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

T Nozawa

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

Y Yasumura

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

N Tanaka

4

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21 September 2019

H Suga

5

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21 September 2019

publication date

1 January 1988

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Europe PubMed Central

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21 September 2019

Heart and Vessels

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

4

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21 September 2019

3

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21 September 2019

153-161

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21 September 2019

Instantaneous Pressure-Volume Relationships and Their Ratio in the Excised, Supported Canine Left Ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A solid-state arteriovenous oxygen difference analyzer for flowing whole blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical efficiency of the left ventricle as a function of preload, afterload, and contractility.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on positive inotropic agents. I. Synthesis of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone and related compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of increase of myocardial oxygen uptake produced by catecholamines1

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hemodynamic effects of a new inotropic agent, OPC-8212, on severe congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Load independence of the instantaneous pressure-volume ratio of the canine left ventricle and effects of epinephrine and heart rate on the ratio.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of OPC-8212, a new positive inotropic agent, and dobutamine on left ventricular global and ischemic regional functions and coronary hemodynamics under coronary artery stenosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode and mechanism of action of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, on the dog heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between oxygen consumption and pressure-volume area of in situ dog heart.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hemodynamic effects of a new positive inotropic agent, 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), in conscious and anesthetized dogs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total mechanical energy of a ventricle model and cardiac oxygen consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of positive inotropic agents on the relation between oxygen consumption and systolic pressure volume area in canine left ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac energetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regression of cardiac oxygen consumption on ventricular pressure-volume area in dog.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of ventricular contractility on non-work-related myocardial oxygen consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemodynamic and electrophysiological effects of a novel positive inotropic drug, OPC-8212, in normal and "failing" guinea pig heart preparations

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism of active calcium transport by sarcoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen cost of electrical activation of the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Digital on-line computation of a predictor of cardiac oxygen consumption. Left ventricular systolic pressure volume area.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of a new positive inotropic agent, 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), on thin bundles of skinned fibers from cardiac muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ventricular systolic pressure-volume area as predictor of cardiac oxygen consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O2 consumption of dog heart under decreased coronary perfusion and propranolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/3248983

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02058428

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3248983%20AND%20SRC:MED&resulttype=core&format=json

21 September 2019

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