Brain Adenosine and Transmitter Amino Acid Release from the Ischemic Rat Cerebral Cortex: Effects of the Adenosine Deaminase Inhibitor Deoxycoformycin (Q68290915)

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scientific article published on 01 February 1991

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English	Brain Adenosine and Transmitter Amino Acid Release from the Ischemic Rat Cerebral Cortex: Effects of the Adenosine Deaminase Inhibitor Deoxycoformycin	scientific article published on 01 February 1991

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scholarly article

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23 September 2019

Brain adenosine and transmitter amino acid release from the ischemic rat cerebral cortex: effects of the adenosine deaminase inhibitor deoxycoformycin (English)

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Brain Adenosine and Transmitter Amino Acid Release from the Ischemic Rat Cerebral Cortex: Effects of the Adenosine Deaminase Inhibitor Deoxycoformycin (English)

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10.1111/J.1471-4159.1991.TB08198.X

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adenosine deaminase inhibitors

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author name string

J. W. Phillis

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G. A. Walter

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R. E. Simpson

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publication date

1 February 1991

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Journal of Neurochemistry

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Alteration of amino acid content of cerebrospinal fluid from patients with epilepsy

1

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2-chloroadenosine attenuates kainic acid-induced toxicity within the rat straitum: relationship to release of glutamate and Ca2+ influx

2

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Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

3

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Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia

4

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Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3

5

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Adenosine decreases aspartate and glutamate release from rat hippocampal slices.

7

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An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus.

8

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Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue

9

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An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus.

10

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Inhibition of [3H] glutamate release from rat hippocampal slices by L-phenylisopropyladenosine.

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Pharmacokinetics of 2'-deoxycoformycin, an inhibitor of adenosine deaminase, in the rat.

12

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MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period

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Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis

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Ischemia-induced shift of inhibitory and excitatory amino acids from intra- to extracellular compartments.

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Low dose of barbiturates for prevention of hippocampal lesions after brief ischemic episodes.

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Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent--in vitro and in vivo evidence

17

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Purine nucleotide metabolism in the cat brain after one hour of complete ischemia.

18

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Concentrations of energy metabolites and cyclic nucleotides during and after bilateral ischemia in the gerbil cerebral cortex

19

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Adenosine agonists reduce voltage-dependent calcium conductance of mouse sensory neurones in cell culture

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Release of glutamate, aspartate, and gamma-aminobutyric acid from isolated nerve terminals

21

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Concentrations of gamma-aminobutyric acid and adenosine in the CSF in progressive myoclonus epilepsy without Lafora's bodies

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The effects of the xanthine oxidase inhibitors, allopurinol and oxypurinol on the pattern of purine release from hypoxic rat cerebral cortex

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Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.

24

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Oxypurinol attenuates ischemia-induced hippocampal damage in the gerbil

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Deoxycoformycin antagonizes ischemia-induced neuronal degeneration

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Hypoxia/hypotension evoked release of glutamate and aspartate from the rat cerebral cortex

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Effect of a brief hypoxic/hypotensive episode on the in vivo release of cerebral cortical gamma-aminobutyric acid and glycine

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Effects of anoxia on cerebral blood flow in the rat brain: evidence for a role of adenosine in autoregulation

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Increases in cerebral cortical perfusate adenosine and inosine concentrations during hypoxia and ischemia

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Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex

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A new model of bilateral hemispheric ischemia in the unanesthetized rat

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Adenosine and related nucleotides alter calcium uptake in depolarized synaptosomes of torpedo electric organ

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Glutamate and the pathophysiology of hypoxic--ischemic brain damage

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Occurrence of a large Ca2+-independent release of glutamate during anoxia in isolated nerve terminals (synaptosomes).

37

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25 October 2022

Differential effect of adenosine on pre- and postsynaptic calcium fluxes.

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2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

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Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

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Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits

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Role for gamma-aminobutyric acid in selective vulnerability in gerbils

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Protective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils

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25 October 2022

American Journal of Physiology

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241

H235

author name string

Winn H. R.

publication date

1981

1 reference

10.1111/J.1471-4159.1991.TB08198.X

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10.1111/J.1471-4159.1991.TB08198.X

1 reference

Europe PubMed Central

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23 September 2019

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Europe PubMed Central

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23 September 2019

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