Regulation of endothelial tissue plasminogen activator and plasminogen activator inhibitor type 1 synthesis by diacylglycerol, phorbol ester, and thrombin (Q68350305)

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scientific article published on 01 July 1990

Language	Label	Description	Also known as
English	Regulation of endothelial tissue plasminogen activator and plasminogen activator inhibitor type 1 synthesis by diacylglycerol, phorbol ester, and thrombin	scientific article published on 01 July 1990

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

Regulation of endothelial tissue plasminogen activator and plasminogen activator inhibitor type 1 synthesis by diacylglycerol, phorbol ester, and thrombin (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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author name string

J Grulich-Henn

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

G Müller-Berghaus

2

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Europe PubMed Central

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23 September 2019

publication date

1 July 1990

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

61

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

38-44

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

Regulation of the synthesis and secretion of plasminogen activators by endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of vascular endothelial cells in the regulation of fibrinolysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histamine stimulates inositol phosphate accumulation via the H1-receptor in cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bradykinin and thrombin effects on polyphosphoinositide hydrolysis and prostacyclin production in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butyrate stimulates tissue-type plasminogen-activator synthesis in cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by cultured human endothelial cells: modulation by thrombin, endotoxin, and histamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of the thrombin-induced release of tissue plasminogen activator from cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sandwich ELISA for t-PA antigen employing a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 and lipopolysaccharide induce an inhibitor of tissue-type plasminogen activator in vivo and in cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin exerts a dual effect on stimulated adenylate cyclase in hamster fibroblasts, an inhibition via a GTP-binding protein and a potentiation via activation of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin stimulates inositol phosphate accumulation and prostacyclin synthesis in human endothelial cells from umbilical vein but not from omentum

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turnover of Inositol Phospholipids and Signal Transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostacyclin synthesis and deacylation of phospholipids in human endothelial cells: comparison of thrombin, histamine and ionophore A23187

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator inhibitor-1 from human endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physicochemical characterization of human S-protein and its function in the blood coagulation system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial cell mitogens derived from retina and hypothalamus: biochemical and biological similarities

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of protein kinase C in cell surface signal transduction and tumour promotion

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin induces serotonin secretion and aggregation independently of inositol phospholipids hydrolysis and protein phosphorylation in human platelets permeabilized with saponin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylcholine is the major phospholipid providing arachidonic acid for prostacyclin synthesis in thrombin-stimulated human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation and desensitization of tissue plasminogen activator release from human endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of thrombin on the production of plasminogen activators and PA inhibitor-1 by human foreskin microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural requirements for diacylglycerols to mimic tumor-promoting phobol diester action on the epidermal growth factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staurosporine, a potent protein kinase C inhibitor, fails to inhibit 12-O-tetradecanoylphorbol-13-acetate-caused ornithine decarboxylase induction in isolated mouse epidermal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of plasminogen activator inhibitor-1 mRNA in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of plasminogen activator activity by phorbol ester in transformed fetal bovine aortic endothelial cells. Possible independence from protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrinolytic system of vascular endothelial cells. Role of plasminogen activator inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Method for the determination of fast acting plasminogen activator inhibitor capacity (PAI-cap) in plasma, platelets and endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-(5-isoquinol inesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase c in rabbit platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2117475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01739432

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2117475%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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