Metabolic profiling of valproic acid in patients using negative-ion chemical ionization gas chromatography-mass spectrometry (Q68350693)

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23 September 2019

title

Metabolic profiling of valproic acid in patients using negative-ion chemical ionization gas chromatography-mass spectrometry (English)

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23 September 2019

author name string

K Kassahun

1

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23 September 2019

K Farrell

2

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23 September 2019

J J Zheng

3

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23 September 2019

F Abbott

4

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23 September 2019

publication date

1 May 1990

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23 September 2019

volume

527

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23 September 2019

issue

2

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23 September 2019

page(s)

327-341

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Rational use of valproate: indications and drug regimen in epilepsy

23 September 2019

cites work

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Clinical pharmacokinetics of valproic acid

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Identification of valproic acid metabolites in human serum and urine using hexadeuterated valproic acid and gas chromatographic mass spectrometric analysis

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7 January 2021

Cytochrome P-450--catalyzed formation of delta 4-VPA, a toxic metabolite of valproic acid

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Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice

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Quantitative structure-anticonvulsant activity relationships of valproic acid, related carboxylic acids and tetrazoles

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7 January 2021

The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies

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Valproate-induced hepatic injury: analyses of 23 fatal cases

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7 January 2021

Capillary gas chromatography-mass spectrometry of valproic acid metabolites in serum and urine using tert.-butyldimethylsilyl derivatives

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7 January 2021

Valproic acid and several metabolites: quantitative determination in serum, urine, breast milk and tissues by gas chromatography-mass spectrometry using selected ion monitoring

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7 January 2021

Quantitative metabolic profiling of valproic acid in humans using automated gas chromatographic/mass spectrometric techniques

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7 January 2021

Negative ion chemical ionization gas chromatography/mass spectrometry of valproic acid metabolites

1 reference

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7 January 2021

Stereoselective synthesis of the diunsaturated metabolites of valproic acid

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7 January 2021

Use of hexadeuterated valproic acid and gas chromatography-mass spectrometry to determine the pharmacokinetics of valproic acid

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7 January 2021

Concentration of metabolites of valproic acid in plasma of epileptic patients

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7 January 2021

Studies on the metabolic fate of valproic acid in the rat using stable isotope techniques

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7 January 2021

The effect of carbamazepine on valproic acid disposition in adult volunteers

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7 January 2021

Penetration of valproate and its active metabolites into cerebrospinal fluid of children with epilepsy

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7 January 2021

10.1016/S0378-4347(00)82116-7

Identifiers

DOI

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23 September 2019

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