Immunosuppressive effects of (2R,5R)-6-heptyne-2,5-diamine an inhibitor of polyamine synthesis: I. Effects on mitogen-induced immunoglobulin production in human cultured lymphocytes (Q68448471)

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scientific article published on 01 April 1988

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English	Immunosuppressive effects of (2R,5R)-6-heptyne-2,5-diamine an inhibitor of polyamine synthesis: I. Effects on mitogen-induced immunoglobulin production in human cultured lymphocytes	scientific article published on 01 April 1988

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scholarly article

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24 September 2019

Immunosuppressive effects of (2R,5R)-6-heptyne-2,5-diamine an inhibitor of polyamine synthesis: I. Effects on mitogen-induced immunoglobulin production in human cultured lymphocytes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3396214%20AND%20SRC:MED&resulttype=core&format=json

24 September 2019

ornithine decarboxylase inhibitors

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A3396214

5 January 2023

author name string

J. L. Pasquali

1

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5 January 2023

P. S. Mamont

2

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5 January 2023

A. Weryha

3

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5 January 2023

A. M. Knapp

4

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5 January 2023

A. Blervaque

5

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5 January 2023

M. Siat

6

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5 January 2023

language of work or name

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5 January 2023

publication date

1 April 1988

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24 September 2019

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/3396214/?tool=EBI

online access status

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5 January 2023

Clinical and Experimental Immunology

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24 September 2019

72

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24 September 2019

1

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24 September 2019

141-144

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24 September 2019

Separation of leukocytes from blood and bone marrow. Introduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IDENTIFICATION OF THE AMINOALDEHYDES PRODUCED BY THE OXIDATION OF SPERMINE AND SPERMIDINE WITH PURIFIED PLASMA AMINE OXIDASE

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine synthesis during lymphocyte activation. Induction of ornithine decarboxylase and S-adenosyl methionine decarboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triggering mechanism of B lymphocytes. II. Induction of ornithine decarboxylase in B cells by anti-immunoglobulin and enhancing soluble factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cellular levels of spermidine or spermine are required for optimal DNA synthesis in lymphocytes activated by concanavalin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The T cell dependence of B cell differentiation induced by pokeweed mitogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the formation of polyamines and macromolecules by dl-α-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in phytohaemagglutinin-activated human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between inhibition of polyamine biosynthesis and DNA replication in activated lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Lymphocyte Proliferation by Polyamines Requires Ruminant-Plasma Polyamine Oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic procedure for the simultaneous determination of the natural polyamines and their monoacetyl derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

(2R,5R)-6-heptyne-2,5-diamine, an extremely potent inhibitor of mammalian ornithine decarboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of mitogens and lymphokines in the induction of ornithine decarboxylase (ODC) in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of (2R, 5R)-6-heptyne-2,5-diamine, a potent inhibitor of L-ornithine decarboxylase, on rat hepatoma cells cultured in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by DL-alpha-difluoromethylornithine of the pokeweed mitogen-induced immunoglobulin production in cultured human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective modulation by alpha-difluoromethylornithine of T-lymphocyte and antibody-mediated cytotoxic responses to mouse tumor allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors controlling the B-cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the biochemistry of polyamines in eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ornithine decarboxylase induction and polyamine biosynthesis are required for the growth of interleukin-2- and interleukin-3-dependent cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased ornithine decarboxylase activity and polyamine biosynthesis are required for optimal cytolytic T lymphocyte induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular polyamine biosynthesis is required for interleukin 2 responsiveness during lymphocyte mitogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The millipore filter assay technique for measuring tritiated thymidine incorporation into DNA in leucocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/3396214

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=3396214

5 January 2023

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3396214%20AND%20SRC:MED&resulttype=core&format=json

24 September 2019

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